112160-32-4

Upstream product

• 1234-35-1 Z-Arg-OH 
• 112160-39-1 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride 
• 78-79-5 isoprene 
• 697-82-5 2,3,5-trimethylphenol 
• 55646-01-0 2,2,5,7,8-pentamethyl-chromane 

Downstream Products

• 120386-74-5 Z-L-Arg(Pmc)-OSu 
• 873460-91-4 Z-Arg(Pmc)-Gly-OMe 
• 796110-60-6 H-Arg(Pmc)-His(Trt)-Leu-NH₂ 
• 119831-72-0 Fmoc-Arg(Pbf)-OH 
• 137043-77-7 N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylleucinyl-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester tosylate 
• 137043-73-3 N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester tosylate 
• 137043-71-1 N^α-<2,2-bis(4'-nitrophenyl)ethoxycarbonyl>-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)arginine 
• 120386-75-6 Z-L-Arg(Pmc)-L-Asn-OH 
• 120386-78-9 Bpoc-L-Lys(Boc)-L-Arg(Pmc)-L-Asn-OH 
• 1224923-50-5 C₃₀H₄₃N₅O₇S 
• 169543-97-9 C₂₈H₃₉N₅O₆S 
• 112160-37-9 (2R)-2-amino-5-{[(2,2,5,7,8-pentamethyl-3,4-dihydro-2H-chromen-6-yl)sulfonyl]carbamimidamido}pentanoic acid 
• 873461-01-9 C₅₅H₇₄N₈O₁₃S 
• 873460-99-2 C₄₉H₇₀N₈O₁₃S 

Relevant academic research and scientific papers

An acid labile arginine derivative for peptide synthesis: N(G)-2,2,5,7,8-pentamethylchroman-6-sulphonyl-L-arginine

A trifluoroacetic acid (TFA) labile protecting group for the guanidine side chain function of arginine has been developed. N(G)-(2,2,5,7,8-Pentamethylchroman-6-sulphonyl-L-arginine is cleaved rapidly in TFA or 50% TFA in dichloromethane at room temperatur

NG-2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULPHONYL-L-ARGININE: A NEW ACID LABILE DERIVATIVE FOR PEPTIDE SYNTHESIS

A new acid labile protecting group for the guanido side chain functionality of arginine has been developed.NG-(2,2,5,7,8-Pentamethylchroman-6-sulphonyl)-L-arginine, prepared from Nα-benzyloxycarbonyl-L-arginine and 2,2,5,7,8-pentamethylchroman-6-sulphonyl chloride, is cleaved rapidly in trifluoroacetic acid (TFA) or 50percent TFA in dichloromethane at room temperature.