112211-91-3Relevant academic research and scientific papers
ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-METHYL CARBONYL COMPOUNDS BY ALDOL REACTION
Ando, Akira,Shioiri, Takayuki
, p. 4969 - 4988 (1989)
The enantioselective aldol reactions of ketone lithium enolates with aldehydes mediated chiral lithium amides were extensively investigated.The chiral amino ethers 4a-4l and diamines 16a,b were prepared from α-amino acids.The reaction conditions and the s
Asymmetric Synthesis using Chiral Bases: Enantioselective α-Alkylation of Carboxylic Acids
Ando, Akira,Shioiri, Takayuki
, p. 656 - 658 (2007/10/02)
Enantioselective alkylation of carboxylic acids (1) and (2) at the α-position can be performed using the chiral lithium isopropylamides (3) or (4), which function as both a strong base and a chiral auxiliary.
