ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-METHYL CARBONYL COMPOUNDS BY ALDOL REACTION

DOI: 10.1016/S0040-4020(01)81078-4

Source and publish data:

Tetrahedron p. 4969 - 4988 (1989)

Update date:2022-08-05

Topics: Synthesis Column chromatography NMR spectroscopy Enantioselective Stereochemistry Chiral Catalyst Aldol Reaction Experimental terms ENOLATE ION

Authors:

Ando, Akira

Shioiri, Takayuki

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Article abstract of DOI:10.1016/S0040-4020(01)81078-4

The enantioselective aldol reactions of ketone lithium enolates with aldehydes mediated chiral lithium amides were extensively investigated.The chiral amino ethers 4a-4l and diamines 16a,b were prepared from α-amino acids.The reaction conditions and the s

Full text of DOI:10.1016/S0040-4020(01)81078-4

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