112256-71-0Relevant academic research and scientific papers
A Synthesis of (3S,4R)-3--4-carboxymethyl-2-azetidinone, the Thienamycin Intermadiate, from (S)-Ethyl Lactate
Ito, Yoshio,Terashima, Shiro
, p. 445 - 448 (2007/10/02)
The title thienamycin intermadiate was efficiently synthesized from (S)-ethyl lactate (3) by subjecting (3S,4S)-32-acetyl-4--2-azetidinone readily obtainable from 3, to sequential reactions in which base catalyzed elimination and reg
A NOVEL SYNTHESIS OF (3R,4R)-4-ACETOXY-3--2-AZETIDINONE, THE VERSATILE KEY INTERMEDIATE OF CARBAPENEM SYNTHESIS, FROM (S)-ETHYL LACTATE
Ito, Yoshio,Kawabata, Takeo,Terashima, Shiro
, p. 5751 - 5754 (2007/10/02)
A highly efficient synthesis of the title compound was accomplished employing the addition of diketene to chiral imine as a key stereoselective reaction and using inexpensive (S)-ethyl lactate as a starting material.
