115026-45-4

Basic information

• Product Name: (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-(1-t-butyldimethylsilyloxy)ethyl>-2-azetidinone
• Synonyms: (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-(1-t-butyldimethylsilyloxy)ethyl>-2-azetidinone
• CAS NO: 115026-45-4
• Molecular Weight: 363.572
• Mol File: 115026-45-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-(1-t-butyldimethylsilyloxy)ethyl>-2-azetidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-(1-t-butyldimethylsilyloxy)ethyl>-2-azetidinone(115026-45-4)
• EPA Substance Registry System: (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-(1-t-butyldimethylsilyloxy)ethyl>-2-azetidinone(115026-45-4)

Safety Data

• Hazardous Substances Data: 115026-45-4(Hazardous Substances Data)

Upstream product

• 115026-43-2 (3S,4S)-3-acetyl-4-<(S)-1-benzyloxyethyl>-1-(di-p-anisylmethyl)-2-azetidinone 
• 126577-34-2 (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(S)-1-hydroxyethyl>-2-azetidinone 
• 54783-72-1 ethyl (S)-2-(benzyloxy)propionate 
• 115026-44-3 3-Acetyl-1-[bis-(4-methoxy-phenyl)-methyl]-4-[(S)-1-(1-ethoxy-ethoxy)-ethyl]-azetidin-2-one 
• 127200-96-8 1-[Bis-(4-methoxy-phenyl)-methyl]-3-(1,1-dimethoxy-ethyl)-4-((S)-1-hydroxy-ethyl)-azetidin-2-one 
• 115026-42-1 [(S)-2-Benzyloxy-prop-(E)-ylidene]-[bis-(4-methoxy-phenyl)-methyl]-amine 
• 100-39-0 benzyl bromide 
• 127254-18-6 [(S)-2-Benzyloxy-prop-(E)-ylidene]-[bis-(4-methoxy-phenyl)-methyl]-amine 
• 122151-32-0 (S)-2-(benzyloxy)-1-(pyrrolidin-1-yl)propan-1-one 
• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 115075-46-2 (3S,4S)-4-<(S)-1-benzyloxyethyl>-1--3-<(S)-1-hydroxyethyl>-2-azetidinone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 112256-71-0 (3S,4S)-4-<(S)-1-benzyloxyethyl>-3-<(R)-1-hydroxyethyl>-2-azetidinone 

Downstream Products

• 118735-54-9 Toluene-4-sulfonic acid (S)-1-{(2S,3S)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-ethyl ester 
• 118735-54-9 (3S,4S)-3-<(R)-1-(t-butyldimethylsilyloxy)ethyl>4-<(S)-1-(p-toluenesulfonyloxy)ethyl>-2-azetidinone 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 

Relevant articles and documents

Novel syntheses of the carbapenem key intermediates, (3R,4R)-4-acetoxy 3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone and (3S,4R)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-carboxymethyl-2- azetidinone, from (S)-ethyl lactate

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A Synthesis of (3S,4R)-3--4-carboxymethyl-2-azetidinone, the Thienamycin Intermadiate, from (S)-Ethyl Lactate

The title thienamycin intermadiate was efficiently synthesized from (S)-ethyl lactate (3) by subjecting (3S,4S)-32-acetyl-4--2-azetidinone readily obtainable from 3, to sequential reactions in which base catalyzed elimination and reg