112375-41-4Relevant academic research and scientific papers
Enzymes in organic synthesis. 27: Lipase-catalyzed synthesis of (5R,6S)-6-acetoxyalkan-5-olides - Homologues of the mosquito oviposition attractant pheromone
Henkel,Kunath,Schick
, p. 434 - 440 (2007/10/03)
Sixteen homologous (5R*,6S*)-6-hydroxyalkan-5-olides rac-5 and their acetoxy derivatives rac-6 were synthesized from the corresponding methyl (Z)-alk-5-enoates 3 by osmium(VIII) oxide catalyzed cis-hydroxylation to the dihydroxy esters rac-4 and hydrolysi
The Capsaicinoids: Their Separation, Synthesis, and Mutagenicity
Gannett, Peter M.,Nagel, Donald L.,Reilly, Pam J.,Lawson, Terence,Sharpe, Jody,Toth, Bela
, p. 1064 - 1071 (2007/10/02)
Capsaicin (1b), the pungent ingredient in many varietes of Capsicums has recently been implicated as a possible carcinogen.When obtained from natural sources 1b is always accompanied by a number of related homologues.We have isolated seven of these homologues, characterized them, and synthesized them by a general and unique route developed in our laboratories.Also reported are mutagenicity data for 1b and an extract of red pepper as measured by the Ames assay and the V-79 mammalian cell assay.
