1125-25-3

Basic information

• Product Name: Benzenethiosulfonic acid S-methyl ester
• Synonyms: Benzenethiosulfonic acid S-methyl ester
• CAS NO: 1125-25-3
• Molecular Formula: C₇H₈O₂S₂
• Molecular Weight: 0
• Mol File: 1125-25-3.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenethiosulfonic acid S-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenethiosulfonic acid S-methyl ester(1125-25-3)
• EPA Substance Registry System: Benzenethiosulfonic acid S-methyl ester(1125-25-3)

Safety Data

• Hazardous Substances Data: 1125-25-3(Hazardous Substances Data)

Usage

General Description

Benzenethiosulfonic acid S-methyl ester is an organic compound with the chemical formula C8H10O3S2. It is a methyl ester derivative of benzenethiosulfonic acid, a compound that contains a sulfur atom and a sulfonic acid group attached to a benzene ring. This chemical is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in organic reactions and as a reagent in chemical research. It is important to handle benzenethiosulfonic acid S-methyl ester with care, as it is a corrosive substance that can cause irritation to the skin, eyes, and respiratory tract if not properly handled.

Upstream product

• 14173-25-2 methyl phenyl disulfide 
• 1887-29-2 sodium phenylthiosulfonate 
• 873-55-2 sodium benzenesulfonate 
• 63911-24-0 S-methyl benzenethiosulfinate 
• 20277-69-4 sodium methansulfinate 
• 882-33-7 diphenyldisulfane 
• 108-98-5 thiophenol 
• 74-88-4 methyl iodide 
• 624-92-0 Dimethyldisulphide 
• 77-78-1 dimethyl sulfate 
• 75-65-0 tert-butyl alcohol 
• 67-63-0 isopropyl alcohol 
• 64-17-5 ethanol 
• 16599-39-6 benzenethiosulfonic acid ; potassium-salt 

Downstream Products

• 858835-74-2 1-benzenesulfonyl-1-methylsulfanyl-acetone 

Relevant articles and documents

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling Reaction of gem-Difluoroalkenes with Thiosulfonate or Selenium Sulfonate

A nickel-catalyzed defluorinative reductive cross-coupling of gem-difluoroalkenes with thiosulfonate or selenosulfonates is described. The reaction involves the formation of thiolated or selenylated monofluoroolefins via regioselective C-F bond cleavage and C-S or C-Se bond formation and features easily available substrates, mild reaction conditions, and high E-selectivity. One of the derivatives by further cross coupling with PhMgBr exhibited an aggregation-induced emission enhancement effect.

Visible-Light-Induced Cyclization/Aromatization of 2-Vinyloxy Arylalkynes: Synthesis of Thio-Substituted Dibenzofuran Derivatives

A visible-light-induced cascade reaction of 2-vinyloxy arylalkynes with thiosulfonates was developed and provided unexpected thio-substituted dibenzofuran derivatives in moderate yields. Mechanistic studies revealed the thiosulfonylation product of 2-vinyloxy arylalkyne was the key intermediate, and the additive disulfide played the role of hydrogen abstraction in the aromatization process to offer the desired product. This reaction presents a new reaction mode for the construction of polycyclic oxygen heterocycles.

Gold/photoredox-cocatalyzed atom transfer thiosulfonylation of alkynes: Stereoselective synthesis of vinylsulfones

We report a gold and photoredox combined radical approach for the rapid synthesis of thio-functionalized vinylsulfones from alkynes. Key features of this method include very mild conditions, broad substrate scope, excellent regio- and stereoselectivties, and 100% atom economy.