112561-41-8Relevant articles and documents
TOTAL SYNTHESIS OF LYNGBYATOXIN A (TELEOCIDIN A-1) AND TELEOCIDIN A-2
Muratake, Hideaki,Natsume, Mitsutaka
, p. 2265 - 2268 (1987)
An eleven step synthesis of tumor promoters, lyngbyatoxin A (=teleocidin A-1) (1) and teleocidin A-2 (2) was achieved from 1-tosylpyrrole (4) using a novel reaction forming 7-alkyl-4-aminoindoles (11).
PREPARATION OF ALKYL-SUBSTITUTED INDOLES IN THE BENZENE PORTION. Part 3
Muratake, Hideaki,Natsume, Mitsutaka
, p. 683 - 690 (2007/10/02)
Three-step synthesis of 7- and 4-alkyl-1-tosylindoles (9 and 10) was accomplished by combination of the Friedel-Crafts acylation of 4, and the treatment of 7 and 8 with H2SO4 in 2-propanol as illustrated in Chart 2.Further a novel synthetic method of 16 was devised from 14 by way of 15.