112561-43-0

Basic information

• Product Name: Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate
• Synonyms: Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate
• CAS NO: 112561-43-0
• Molecular Weight: 448.54
• Mol File: 112561-43-0.mol

Chemical Properties

• CAS DataBase Reference: Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate(112561-43-0)
• EPA Substance Registry System: Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate(112561-43-0)

Safety Data

• Hazardous Substances Data: 112561-43-0(Hazardous Substances Data)

Upstream product

• 112561-41-8 Ethyl 4-<1-(4-methylphenylsulfonyl)-2-pyrrolyl>-4-oxobutanoate 
• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 112561-42-9 4-<1-<(4-Methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutyric acid 
• 33099-10-4 Methyl N-methyl-L-valinate hydrobromide 

Downstream Products

• 138424-20-1 Methyl N-<5,5-dimethyl-4-hydroxy-4-(2-pyrrolyl)-6-heptenoyl>-N-methyl-L-valinate 
• 138424-21-2 Methyl N-<(E)-4-hydroxy-4-(2-pyrrolyl)-5,9,13-trimethyl-5-vinyl-8,12-tetradecadienoyl>-N-methyl-L-valinate 
• 119375-01-8 (-)-pendolmycin 
• 119375-01-8 12-Epipendolmycin 

Relevant articles and documents

Synthesis of teleocidins A, B and their congeners. Part 1. An efficient synthesis method of N-(7-alkyl-4-indolyl)-N-methyl-L-valine esters, essential intermediates for teleocidin synthesis

Details of the synthesis method of N-[7-(3,7-dimethyl-1,6-octadien-3-yl)-4-indolyl]-N-methyl-L-valine esters 19 and 20, essential precursors for the tumor promotes lyngbyatoxin A (= teleocidin A-1) (2) and teleocidin A-2 (3) are presented. Key reaction st

TOTAL SYNTHESIS OF LYNGBYATOXIN A (TELEOCIDIN A-1) AND TELEOCIDIN A-2

An eleven step synthesis of tumor promoters, lyngbyatoxin A (=teleocidin A-1) (1) and teleocidin A-2 (2) was achieved from 1-tosylpyrrole (4) using a novel reaction forming 7-alkyl-4-aminoindoles (11).