112561-42-9

Upstream product

• 108-30-5 succinic acid anhydride 
• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 98-59-9 p-toluenesulfonyl chloride 
• 112561-41-8 Ethyl 4-<1-(4-methylphenylsulfonyl)-2-pyrrolyl>-4-oxobutanoate 

Downstream Products

• 138424-46-1 Methyl N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate 
• 112561-43-0 Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate 
• 138424-63-2 Methyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-D-valinate 
• 131226-12-5 t-Butyl N-methyl-N-<4-<1-<(4-methylphenyl)sulfonyl>-2-pyrrolyl>-4-oxobutanoyl>-L-valinate 

Relevant academic research and scientific papers

Design of chiral poly(pyrroles)

The synthesis of three 3-substituted and one N-substituted chiral pyrrole derivatives as well as their electropolymerization conditions are described. The new materials thus obtained possess recognition properties as enantioselective electrodes.

Total synthesis of indole alkaloid pendolmycin

The teleocidin class of an indole alkaloid, pendolmycin (1) was synthesized from 1-(4-methylphenylsulfonyl)pyrrole in thirteen steps by way of the indole derivative (16), the amino- diester compound (6), and the ethyl carboxylate (5).

TOTAL SYNTHESIS OF LYNGBYATOXIN A (TELEOCIDIN A-1) AND TELEOCIDIN A-2

An eleven step synthesis of tumor promoters, lyngbyatoxin A (=teleocidin A-1) (1) and teleocidin A-2 (2) was achieved from 1-tosylpyrrole (4) using a novel reaction forming 7-alkyl-4-aminoindoles (11).