1125828-26-3 Usage
Description
1-(2-Bromo-5-chlorophenyl)-3-methyl-1H-pyrazole, a member of the pyrazole family of drugs, is a chemical compound with the molecular formula C9H7BrClN2. It is known for its potential pharmacological properties and is often utilized in research and development. 1-(2-BroMo-5-chlorophenyl)-3-Methyl-1H-pyrazole has the capacity to act as an enzyme inhibitor, influencing various physiological processes, and is under investigation for its possible therapeutic applications, although further studies are required to ascertain its full effects and uses. It may also find applications in organic chemistry and chemical synthesis.
Uses
Used in Pharmaceutical Research and Development:
1-(2-Bromo-5-chlorophenyl)-3-methyl-1H-pyrazole is used as a research compound for its potential pharmacological properties, particularly for its ability to act as an enzyme inhibitor. This makes it a candidate for the development of new drugs targeting specific physiological processes.
Used in Organic Chemistry and Chemical Synthesis:
In the field of organic chemistry, 1-(2-Bromo-5-chlorophenyl)-3-methyl-1H-pyrazole may be employed as a reagent or intermediate in the synthesis of other complex organic molecules, contributing to the advancement of chemical research and the creation of novel compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1125828-26-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,5,8,2 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1125828-26:
(9*1)+(8*1)+(7*2)+(6*5)+(5*8)+(4*2)+(3*8)+(2*2)+(1*6)=143
143 % 10 = 3
So 1125828-26-3 is a valid CAS Registry Number.
1125828-26-3Relevant articles and documents
Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors
Aiello, Robert,Barucci, Nicole,Bourassa, Patricia,Goldberg, Daniel R.,Paralkar, Vishwas,Valentine, James,Zavadoski, William,Zhang, Qing,De Lombaert, Stéphane
supporting information, p. 1124 - 1129 (2020/04/09)
The central role of the biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) as a neurotransmitter with important cognitive and behavioral functions is well known. However, 5-HT produced in the brain only accounts for approximately 5% of the total amount of 5-HT generated in the body. At the onset of our work, it appeared that substituted phenylalanine derivatives or related aryl amino acids were required to produce potent inhibitors of TPH1, as significant losses of inhibitory activity were noted in the absence of this structural element. We disclose herein the discovery of a new class of TPH1 inhibitors that significantly lower peripherally 5-HT.
METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS
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Page/Page column 6-7, (2009/04/24)
Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
