112708-89-1 Usage
General Description
(1S,2R)-2-(MethylaMino)-Cyclohexanol is a chiral compound with the molecular formula C7H15NO. It is also known as pseudoephedrine, and it is commonly used as a decongestant and nasal decongestant in over-the-counter medications. The compound works by shrinking the blood vessels in the nasal passages, which helps to relieve congestion and improve breathing. Pseudoephedrine is a sympathomimetic amine, meaning it acts on the sympathetic nervous system to produce its effects. It is typically administered orally in the form of tablets or capsules, and it is generally well-tolerated when used as directed, although it can cause side effects such as increased heart rate, nervousness, and anxiety in some individuals. Due to its potential for abuse and its use in the illicit production of methamphetamine, pseudoephedrine is subject to strict regulations in many countries.
Check Digit Verification of cas no
The CAS Registry Mumber 112708-89-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,7,0 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 112708-89:
(8*1)+(7*1)+(6*2)+(5*7)+(4*0)+(3*8)+(2*8)+(1*9)=111
111 % 10 = 1
So 112708-89-1 is a valid CAS Registry Number.
112708-89-1Relevant articles and documents
Resolution of racemic 2-aminocyclohexanol derivatives and their application as ligands in asymmetric catalysis
Schiffers, Ingo,Rantanen, Toni,Schmidt, Frank,Bergmans, Werner,Zani, Lorenzo,Bolm, Carsten
, p. 2320 - 2331 (2007/10/03)
A preparatively easy and efficient protocol for the resolution of racemic 2-aminocyclohexanol derivatives is described, delivering both enantiomers with >99% enantiomeric excess (ee) by sequential use of (R)- and (S)-mandelic acid. A simple aqueous workup procedure permits the isolation of the amino alcohols in analytically pure form and the almost quantitative recovery of mandelic acid. Debenzylation of enantiopure trans-2-(N-benzyl)amino-1- cyclohexanol by hydrogenation and subsequent derivatization give access to a broad variety of diversely substituted derivatives. Furthermore, the corresponding cis isomers are readily available. Applications of these optically active aminocyclohexanols in catalyzed asymmetric phenyl transfer reactions to benzaldehydes and transfer hydrogenations of aryl ketones lead to products with up to 96% ee.
