112775-40-3

Basic information

• Product Name: {(2R,3S)-3-[(4R,5S)-5-((E)-(R)-11-Benzyloxy-dodec-1-en-8-ynyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranylmethoxy}-tert-butyl-dimethyl-silane
• CAS NO: 112775-40-3
• Molecular Weight: 556.858
• Mol File: 112775-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2R,3S)-3-[(4R,5S)-5-((E)-(R)-11-Benzyloxy-dodec-1-en-8-ynyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranylmethoxy}-tert-butyl-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: {(2R,3S)-3-[(4R,5S)-5-((E)-(R)-11-Benzyloxy-dodec-1-en-8-ynyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranylmethoxy}-tert-butyl-dimethyl-silane(112775-40-3)
• EPA Substance Registry System: {(2R,3S)-3-[(4R,5S)-5-((E)-(R)-11-Benzyloxy-dodec-1-en-8-ynyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranylmethoxy}-tert-butyl-dimethyl-silane(112775-40-3)

Safety Data

• Hazardous Substances Data: 112775-40-3(Hazardous Substances Data)

Upstream product

• 112775-33-4 (4R,5S)-5-[(2S,3R)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-oxiranyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 112775-39-0 ((R)-10-Benzyloxy-undec-7-ynyl)-triphenyl-phosphonium; bromide 
• 110-53-2 1-Bromopentane 
• 50622-09-8 2,3-O-isopropylidene-L-threitol 
• 81028-13-9 (E)-3-<(4S-trans)-2,2-dimethyl-5-<(phenylmethoxy)methyl>-1,3-dioxolan-4-yl>-2-propenol 
• 81076-16-6 [(2R,3S)-3-((4R,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-oxiranyl]-methanol 
• 112775-37-8 Toluene-4-sulfonic acid (R)-10-benzyloxy-undec-7-ynyl ester 
• 112775-35-6 2-((R)-10-Benzyloxy-undec-7-ynyloxy)-tetrahydro-pyran 
• 112775-38-9 ((R)-10-Bromo-1-methyl-dec-3-ynyloxymethyl)-benzene 
• 112775-36-7 (R)-10-Benzyloxy-undec-7-yn-1-ol 
• 112775-32-3 {(4S,5R)-5-[(2S,3R)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-oxiranyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol 
• 112775-34-5 (R)-11-(Tetrahydro-pyran-2-yloxy)-undec-4-yn-2-ol 
• 90661-39-5 (E)-ethyl 3-((4S,5S)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 
• 81028-12-8 (4S,5R)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-5-carboxaldehyde 

Relevant articles and documents

STEREOCONTROLLED TOTAL SYNTHESIS OF THE MACROCYCLIC LACTONE (-)-ASPICILIN

The essential features of the enantiocontrolled total synthesis of (-)-aspicilin are the strategic use of the photochemical rearrangement of α,β-epoxy diazomethyl ketones to 4-hydroxyalkenoates (Scheme 1) and the stereochemical control of the Sharpless epoxidation, α,ο functionalization of an alkynol using potassium 3-aminopropylamine (KAPA) as acetylene zipper, coupling between C7 and C8 by means of a Wittig reaction and lactonization by using 2,6-dichlorobenzoyl chloride.