112880-83-8

Basic information

• Product Name: 2-NITRO-5-PHENOXYTOLUENE
• Synonyms: 2-NITRO-5-PHENOXYTOLUENE;2-Methyl-1-nitro-4-phenoxybenzene;2-NITRO-5-PHENOXYTOLUENE(WXC09198)
• CAS NO: 112880-83-8
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 229.23134
• Mol File: 112880-83-8.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 329°Cat760mmHg
• Flash Point: 138.4°C
• Appearance: /
• Density: 1.218g/cm³
• Vapor Pressure: 0.00035mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-NITRO-5-PHENOXYTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-5-PHENOXYTOLUENE(112880-83-8)
• EPA Substance Registry System: 2-NITRO-5-PHENOXYTOLUENE(112880-83-8)

Safety Data

• Hazardous Substances Data: 112880-83-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H11NO3/c1-10-9-12(7-8-13(10)14(15)16)17-11-5-3-2-4-6-11/h2-9H,1H3

Upstream product

• 108-95-2 phenol 
• 446-33-3 5-Fluoro-2-nitrotoluene 
• 2581-34-2 3-methyl-4-nitrophenol 
• 12775-96-1 copper 

Downstream Products

• 163258-52-4 5-(4-bromophenoxy)-2-nitrotoluene 
• 157060-89-4 trans-1-<2-(N,N-dimethylamino)ethenyl>-5-phenoxy-2-nitrobenzene 

Relevant articles and documents

Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity

Bruton's tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase that plays a critical role in the activation of B cells, macrophages, and osteoclasts. Given the key role of these cell types in the pathology of autoimmune disorders, BTK inhibitors have the

INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE

The present disclosure is directed to compounds of Formula (I) and methods of their use and preparation, as well as compositions comprising compounds of Formula (I).

POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE

The present disclosure is directed to compounds of Formula (I) as Bruton's kinase inhibitors and their preparation, as well as compositions comprising compounds of Formula (I).