113209-88-4

Basic information

• Product Name: Pyridine, 5-fluoro-2-methyl-4-nitro-, 1-oxide
• Synonyms: Pyridine, 5-fluoro-2-methyl-4-nitro-, 1-oxide;5-Fluoro-2-methyl-4-nitropyridine N-oxide;5-Fluoro-2-Methyl-4-nitropyridine 1-Oxide;5-Fluoro-4-nitro-2-picoline N-oxide;5-fluoro-2-methyl-4-nitro-1-oxidopyridin-1-ium
• CAS NO: 113209-88-4
• Molecular Formula: C6H5FN2O3
• Molecular Weight: 172.115
• Mol File: 113209-88-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 422.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.48±0.1 g/cm3(Predicted)
• PKA: -1.89±0.10(Predicted)
• CAS DataBase Reference: Pyridine, 5-fluoro-2-methyl-4-nitro-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 5-fluoro-2-methyl-4-nitro-, 1-oxide(113209-88-4)
• EPA Substance Registry System: Pyridine, 5-fluoro-2-methyl-4-nitro-, 1-oxide(113209-88-4)

Safety Data

• Hazardous Substances Data: 113209-88-4(Hazardous Substances Data)

Usage

General Description

Pyridine, 5-fluoro-2-methyl-4-nitro-1-oxide is a chemical compound with the molecular formula C6H5FN2O3. It is a nitro compound that contains a pyridine ring, with a fluorine atom attached at the 5th position and a methyl group at the 2nd position. The compound also has a nitro group at the 4th position, which is oxidized to form a nitro oxide. This chemical is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is known for its diverse range of applications in organic chemistry and biochemistry due to its unique chemical structure.

Upstream product

• 31181-53-0 2‐methyl‐5‐fluoropyridine 
• 80287-53-2 5-Amino-2-methylpyridine 
• 45673-79-8 2‐methyl‐5‐fluoropyridine 1‐oxide 

Downstream Products

• 102625-91-2 5-methoxy-2-methyl-4-nitro-pyridine-1-oxide 
• 113209-90-8 4-chloro-5-fluoro-2-(hydroxymethyl)pyridine 
• 113209-89-5 4-chloro-5-fluoro-2-methylpyridin-1-ium-1-olate 

Relevant articles and documents

Assessing multiple conformations of lanthanide binding tags for proteins using a sensitive19F-reporter

Quantifying the isomeric species of metal complexes in solution is difficult.19F NMR herein was used to determine the abundance of isomeric species and dynamic properties of lanthanide binding tags. The results suggest that19F is an efficient reporter in assessing and screening paramagnetic tags suitable for protein NMR analysis.

NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

BICYCLIC PROLINE COMPOUNDS

The invention is concerned with the compounds of formula (I) and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.