113241-58-0

Usage

Chemical Family

2(1H)-Quinazolinone

Functional Group

4-(4-fluorophenyl)

Potential Biological Activities

Yes

Potential Pharmaceutical Activities

Yes

Role in Drug Development

Implicated in research for new drug and bioactive molecule development

Importance in Medicinal Chemistry

Interesting subject for further investigation due to its structure and potential reactivity.

Upstream product

• 41534-70-7 (2-cyanophenyl)carbamic acid ethyl ester 
• 352-13-6 4-flourophenylmagnesium bromide 
• 541-41-3 chloroformic acid ethyl ester 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1885-29-6 anthranilic acid nitrile 

Relevant academic research and scientific papers

Biomimetic Asymmetric Reduction of Quinazolinones with Chiral and Regenerable NAD(P)H Models

A facile approach to chiral dihydroquinazolinone derivatives has been described via biomimetic asymmetric reduction of quinazolinones with chiral and regenerable NAD(P)H models. The utility of this method was demonstrated by a concise synthesis of the bromodomain protein divalent inhibitor.

Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders

This invention relates to compounds of the formula 1 wherein R1, R2, and R3 and R4 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system disorders.