113446-15-4

Upstream product

• 54561-18-1 ((1S,2R)-1-Bromo-2-phenyl-cyclopropyl)-phenyl-methanol 
• 100-52-7 benzaldehyde 
• 3234-51-3 1,1-dibromo-2-phenylcyclopropane 

Downstream Products

• 113446-20-1 1,4-diphenyl-4-methoxy-1-butanone 
• 1145-91-1 cis-(2-phenylcyclopropyl)(phenyl)methanone 
• 112252-72-9 E-1-benzoyl-2-phenyl-1-phenylthiocyclopropane 
• 495-71-6 phenacylacetophenone 
• 112252-72-9 Z-1-benzoyl-2-phenyl-1-phenylthiocyclopropane 
• 955-83-9 2,5-diphenylfuran 
• 1145-92-2 (1SR,2SR)-phenyl(2-phenylcyclopropyl)ketone 
• 108401-98-5 2-Isopropoxy-2,5-diphenyl-2,3-dihydro-furan 

Relevant academic research and scientific papers

COMPETITION OF REDUCTIVE DEHALOGENATION, ABSTRACTION-ADDITION, AND FAVORSKII REARRANGEMENT IN THE REACTION OF α-BROMOCYCLOPROPYL KETONES WITH SODIUM ALCOHOLATES

Oxidation of the corresponding α-bromocyclopropylcarbinols gave 7-exo-bromo-7-endo-benzoylbicycloheptane, E-1-bromo-1-benzoyl-2-phenylcyclopropane, E-1-bromo-1-benzoyl-2-butylcyclopropane, E-1-bromo-1-acetyl-2-phenylcyclopropane, and 7-exo-bromo-7-endo-acetylbicycloheptane and the reactions of these compounds with sodium alcoholates were studied.Depending on the structure of the starting α-bromocyclopropyl ketone, the alcoholate used, and the solvent, the predominant reaction is reductive dehalogenation, Favorskii rearrangement or abstraction-addition.In the latter case, 2-alkoxycyclopropyl ketone intermediates are isomerized to 4,5-dihydrofuran derivatives.