113446-20-1Relevant academic research and scientific papers
OPENING OF THE CYCLOPROPANE RING IN α-BROMOCYCLOPROPYL KETONES BY THE ACTION OF TRIPHENYLPHOSPHINE
Kulinkovich, O. G.,Tischenko, I. G.,Sviridov, S. V.
, p. 885 - 888 (2007/10/02)
The reaction of a series of α-bromocyclopropyl ketones substituted in the three-membered ring with triphenylphosphine in alcohols in the presence of catalytic amounts of hydrochloric acid leads to the formation of the products from opening of the cyclopropane ring.Under analogous conditions 1-benzoyl-1-bromocyclopropane undergoes reductive dehalogenation.In boiling methanol 7-exo-benzobicycloheptane is converted into trans-1-bromo-2-benzoylmethylcyclohexane by the action of a mixture of triphenylphosphine and 1-benzoyl-1-bromocyclopropane and also by a mixture of triphenylphosphine and carbon tetrabromide.
