113449-33-5Relevant articles and documents
Divergent Synthesis of Highly Substituted Pyridines and Benzenes from Dienals, Alkynes, and Sulfonyl Azides
Luo, Han,Li, You,Du, Luan,Xin, Xiaolan,Wang, Tao,Han, Jingpeng,Tian, Yi,Li, Baosheng
supporting information, p. 7883 - 7887 (2021/10/20)
Divergent synthesis is extremely important for the highly efficient preparation of structurally diverse target molecules. Herein, we describe a multicomponent cascade reaction, which allows access to highly substituted pyridines and benzenes by combining four individual steps in a one-pot manner from the same set of readily available starting materials. The azepine intermediates were first used as the precursors for 6π-electrocyclization to construct highly substituted pyridines and benzenes in a tunable manner.
Metal-free nitrogenation of 2-acetylbiphenyls: Expeditious synthesis of phenanthridines
Tang, Conghui,Yuan, Yizhi,Jiao, Ning
supporting information, p. 2206 - 2209 (2015/05/13)
An intermolecular nitrogenation reaction toward the synthesis of phenanthridines has been developed. This metal-free protocol provides a novel nitrogen-incorporation transformation using azides as the nitrogen source. Phenanthridines, which are of great interest in pharmaceutical and medicinal chemistry, are synthesized efficiently in one step. Moreover, the byproducts derived from the Schmidt reaction are inhibited, which further demonstrated the high chemoselectivity of this transformation.
Synthesis of 4-(4'-Chlorophenyl)-5-phenyl-1,2-dihydronaphthalene
Cosmo, Robert,Sternhell, Sever
, p. 1499 - 1509 (2007/10/02)
BF3-catalysed cyclization reactions of 1-(biphenyl-2'-yl)-1-(4"-chlorophenyl)but-3-en-1-ol yielded none of the desired title compound but only 9-(4'-chlorophenyl)-10-ethylphenanthrene and 9-allyl-9-(4'-chlorophenyl)fluorene by alternative cyclization path