113454-58-3Relevant articles and documents
Synthesis of CF3-substituted 1,2,3,4-tetrahydroisoquinolines and 1,2,3,6-tetrahydropyridines
Chernyshov, I. Yu.,Levin,Dilman,Belyakov,Struchkova,Tartakovsky
, p. 2102 - 2107 (2011/06/26)
A three-step method for the preparation of CF3-substituted 1,2,3,4-tetrahydroisoquino-lines and 1,2,3,6-tetrahydropyridines has been suggested. The first step includes alkylation of isoquinoline or 4-methylpyridine at the nitrogen atom with the
Stereoselective intermolecular hydride shift mechanism of the new reduction of benzylic alcohols with acid
Kihara, Masaru,Andoh, Junichi,Yoshida, Chiaki
, p. 2473 - 2476 (2007/10/03)
A stereoselective intermolecular hydride shift mechanism of the new reduction reaction of the benzylic hydroxy group of 4-hydroxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline (1) to the corresponding alkane (2) with acid was proved by reaction of the deuterated derivatives (5 and 6) of 1.