113515-72-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester is used as a building block for the synthesis of various drugs and pharmaceuticals. Its quinoline core structure provides a foundation for the development of antimicrobial, antiviral, and anti-inflammatory drugs, making it a valuable component in medicinal chemistry.
Used in Antimicrobial Applications:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester is used as a precursor in the development of antimicrobial agents, targeting a wide range of bacteria and other microorganisms. Its quinoline structure allows for the design of compounds with potent antimicrobial activity, contributing to the fight against drug-resistant infections.
Used in Antiviral Applications:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester is used as a starting material for the synthesis of antiviral drugs. Its quinoline core can be modified to create compounds with antiviral properties, offering potential treatments for various viral infections.
Used in Anti-inflammatory Applications:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester is used as a component in the development of anti-inflammatory drugs. Its quinoline structure can be tailored to produce compounds with anti-inflammatory effects, providing potential therapeutic options for various inflammatory conditions.
Used in Material Science:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester may have applications in the development of new materials, such as organic semiconductors or other functional materials, due to its unique chemical properties and quinoline core.
Used in Agrochemicals:
4-Chloro-8-ethylquinoline-3-carboxylic acid ethyl ester may also find use in the agrochemical industry, where it can be employed as a building block for the synthesis of new pesticides or other agrochemical products, leveraging its quinoline structure for enhanced activity.
In Laboratory Settings:
The ethyl ester form of 4-Chloro-8-ethylquinoline-3-carboxylic acid allows for easier handling and manipulation in laboratory settings, facilitating research and development processes in various scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 113515-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,5,1 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 113515-72:
(8*1)+(7*1)+(6*3)+(5*5)+(4*1)+(3*5)+(2*7)+(1*2)=93
93 % 10 = 3
So 113515-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H14ClNO2/c1-3-9-6-5-7-10-12(15)11(8-16-13(9)10)14(17)18-4-2/h5-8H,3-4H2,1-2H3
113515-72-3Relevant academic research and scientific papers
Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors
Zask,Gu,Albright,Du,Hogan,Levin,Chen,Killar,Sung,DiJoseph,Sharr,Roth,Skala,Jin,Cowling,Mohler,Barone,Black,March,Skotnicki
, p. 1487 - 1490 (2007/10/03)
Potent and selective bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors were synthesized by a novel convergent route. Selectivity and efficacy versus MMPs and TACE could be controlled by appropriate substitution on the scaffolds and by variation of the P1′ group. Select compounds were found to be effective in in vivo models of arthritis.
Quinoline amides
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, (2008/06/13)
Compounds of the formula: (wherein Ra represents an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or heteroaryl group; Rb and Rc, which may be the same or different, each represents hydrogen or an optionally substituted alkyl, cyclo- alkyl, cycloalkylalkyl, alkenyl, alkynyl, phenyl or benzyl group, or Rb and Rc together with the nitrogen atom therebetween represent a saturated nitrogen containing heterocyclic ring; and Rd represents a hydrogen atom or an alkyl or alkanoyl group) and the salts thereof are useful as agents for binding to benzodiazepine receptors, and especially possess anxiolytic activity.
Anxiolytic 4-aminoquinoline-3-carboxamides
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, (2008/06/13)
The present invention comprises certain amide derivatives of 4,8-disubstituted quinoline-3-carboxylic acids of formula I; pharmaceutically acceptable salts of the compounds of formula I; pharmaceutical compositions containing a compound of formula I, or a pharmaceutically acceptable salt thereof, for use in the treatment of anxiety; and processes for the manufacture of the compounds of formula I, as well as intermediates for use in such manufacture.
