113592-34-0

Basic information

• Product Name: Benzenebutanoic acid, a-methylene-, methyl ester
• CAS NO: 113592-34-0
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol File: 113592-34-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, a-methylene-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, a-methylene-, methyl ester(113592-34-0)
• EPA Substance Registry System: Benzenebutanoic acid, a-methylene-, methyl ester(113592-34-0)

Safety Data

• Hazardous Substances Data: 113592-34-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 50-00-0 formaldehyd 
• 6628-68-8 ethyl 2-(ethoxycarbonyl)-4-phenylbutanoate 
• 4224-69-5 methyl 2-(bromomethyl)propenoate 
• 100-39-0 benzyl bromide 
• 3709-38-4 2,2-dimethyl-5-phenethyl-[1,3]dioxane-4,6-dione 
• 108-88-3 toluene 
• 770-09-2 benzyltrimethylsilane 
• 38131-57-6 2-benzenesulfonylmethacrylic acid methyl ester 
• 80-62-6 methacrylic acid methyl ester 
• 66310-10-9 N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate 
• 16520-62-0 4-Phenyl-1-butyne 
• 201230-82-2 carbon monoxide 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 113592-35-1 2-[(1-Benzyloxycarbonylamino-ethyl)-methoxy-phosphinoylmethyl]-4-phenyl-butyric acid methyl ester 
• 113592-33-9 2-[(1-Amino-ethyl)-hydroxy-phosphinoylmethyl]-4-phenyl-butyric acid 
• 102617-51-6 methyl 2-(cyclohexylmethyl)acrylate 
• 102617-50-5 3-Cyclohexyl-2-(cyclohexylmethyl)propionsaeure-methylester 
• 124481-69-2 2-Cyclohexylmethyl-4-phenyl-butyric acid methyl ester 

Relevant articles and documents

Room-temperature Pd-catalyzed methoxycarbonylation of terminal alkynes with high branched selectivity enabled by bisphosphine-picolinamide ligand

We report the room-temperature Pd-catalyzed methoxy-carbonylation with high branched selectivity using a new class of bisphosphine-picolinamide ligands. Systematic optimization of ligand structures and reaction conditions revealed the significance of both

Metal-free desilylative C-C bond formation by visible-light photoredox catalysis

A newly developed methodology for the use of organosilanes as radical precursors under metal-free and visible-light conditions is presented. The strong oxidant character of the 9-mesityl-10-methylacridinium salt in its excited state enables the transforma

Cobalt-Catalyzed Cross-Coupling of Grignards with Allylic and Vinylic Bromides: Use of Sarcosine as a Natural Ligand

Sarcosine was discovered to be an excellent ligand for cobalt-catalyzed carbon-carbon cross-coupling of Grignard reagents with allylic and vinylic bromides. The Co(II)/sarcosine catalytic system is shown to perform efficiently when phenyl and benzyl Grignards are coupled with alkenyl bromides. Notably, previously unachievable Co-catalyzed coupling of allylic bromides with Grignards to linearly coupled α-products was also realized with Co(II)/sarcosine catalyst. This method was used for efficient preparation of the key intermediate in an alternative synthesis of the antihyperglycemic drug sitagliptin.