113697-57-7

Upstream product

• 141-97-9 ethyl acetoacetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 17356-08-0 thiourea 
• 109086-77-3 2-(4'-methoxyphenyl)perhydro-1,3-oxazine 
• 14202-31-4 4-methoxybenzaldehyde-1,1-diacetate 
• 100-52-7 benzaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 154867-09-1 ethyl 5-(4-methoxyphenyl)-2-(4-methoxyphenylmethylene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo<3,2-a>pyrimidine-6-carboxylate 
• 324037-46-9 ethyl 4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-1,4-dihydropyrimidine-5-carboxylate 
• 799266-38-9 ethyl 3-methyl-5-(p-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate 
• 1117816-30-4 C₃₁H₂₅ClN₄O₅ 
• 1104612-49-8 4-(4-methoxy-phenyl)-6-methyl-2-pentylsulfanyl-1, 4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 1104612-51-2 4-(4-methoxy-phenyl)-6-methyl-2-tetradecylsulfanyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 1104612-47-6 2-benzylsulfanyl-4-(4-methoxy-phenyl)-6-methyl-1, 4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 1149335-25-0 5-ethoxycarbonyl-6-methyl-4-(4-methoxyphenyl)-2-(2-hydroxy-2-phenylvinyl)-1,4-dihydropyrimidine 
• 324563-96-4 ethyl 3-acetyl-4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 113697-60-2 ethyl 5-(4-methoxyphenyl)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo<3,2-a>pyrimidine-6-carboxylate 
• 300723-21-1 C₂₄H₂₂N₂O₄S 
• 3774-99-0 5-benzylidene-2,4-thiazolidinedione 
• 1254327-32-6 ethyl 1,3-bis(4-morpholinylmethyl)-4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 
• 1254327-27-9 ethyl 1,3-bis(1H-benzimidazol-1-ylmethyl)-4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 

Relevant academic research and scientific papers

Efficient Ce(NO3)3·6H2O-catalyzed solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a β-keto ester or β-diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or -th

Anhydrous magnesium sulfate mediated solvent-free synthesis of dihydropyrimidin-2(1H)-ones at ambient temperature

An anhydrous magnesium sulfate mediated solvent-free protocol is described for the synthesis of dihydropyrimidinones (Biginelli compounds) at ambient temperature. CSIRO 2007.

FeCl36H2O-Catalyzed Conversion of acylals to dihydropyrimidinones under microwave conditions: A new procedure for the Biginelli reaction

FeCl36H2O efficiently catalyzed the three-component condensation reaction of acylals, ethyl acetoacetate, and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in good yields under solvent-free and microwav

Sodium tetrafluoroborate as a new and highly efficient catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones

Sodium tetrafluoroborate (NaBF4) is found to catalyze the three component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields. This met

Calix[8]arene sulfonic acid catalyzed three-component reaction for convenient synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones under ultrasonic irradiation

In this work, the catalytic activity of calix[8]arene sulfonic acid was successfully investigated for the famous Biginelli reaction. Under ultrasonic irradiation, calix[8]arene sulfonic acid could efficiently catalyzed the three-component reaction of alde

Zirconium(IV) 4-sulphophenylethyliminobismethylphosphonate as an efficient and reusable catalyst for one-pot synthesis of 3,4-dihydropyrimidones under solvent-free conditions

Zirconium(IV) 4-sulphophenylethyliminobismethylphosphonate (ZSBEDP) was prepared and characterised by elemental analysis, IR, TG-DSC, and XRD. ZSBEDP was found to be an efficient catalyst for the Biginelli reaction of aromatic aldehyde, ethyl acetoacetate

3,4-Hydropyrimidin-2-(1H)one derivatives: Solid silica-based sulfonic acid catalyzed microwave-assisted synthesis and their biological evaluation as antihypertensive and calcium channel blocking agents

Microwave assisted simple, efficient procedure for one-pot Biginelli condensation reaction of aldehydes, β-ketoesters, and urea or thiourea in solvent-free condition employing solid silica-based sulfonic acid as a novel, heterogeneous reusable catalyst is

Iron (III) phosphate dihydrate - Catalyzed one-pot synthesis of dihydropyrimidinones and thiones: An improved procedure for the Biginelli reaction

A fast and high yielding one-pot synthesis of 3,4-dihydropyrimidin-2(1H)- ones with various aliphatic and aromatic aldehydes using FePO 4.2H2O as heterogeneous catalyst was carried out in acetonitrile.

Synthesis of 1-alkyl triazolium triflate room temperature ionic liquids and their catalytic studies in multi-component Biginelli reaction

Synthesis of three Brnsted acid-based ionic liquids, namely, 1-ethyl-1,2,4-triazolium triflate (1a), 1-propyl-1,2,4-triazolium triflate (1b) and 1-butyl-1,2,4-triazolium triflate (1c), is described. These ionic liquids have been employed as catalysts for

Bismuth subnitrate catalyzed efficient synthesis of 3,4-dihydropyrimidin- 2(1H)-ones: An improved protocol for the Biginelli reaction

An efficient synthesis of 3,4-dihydropyrimidinones (DHPMs) using bismuth subnitrate as the catalyst for the first time from an aldehyde, β-ketoester, and urea in acetonitrile is described. This new method consistently has the advantage of excellent yields