113772-13-7

Usage

Uses

Used in Organic Synthesis:
METHYL 2-CYANO-2-(2-NITROPHENYL)ACETATE is used as a synthetic intermediate for the production of various organic compounds. Its unique chemical structure allows it to be a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, METHYL 2-CYANO-2-(2-NITROPHENYL)ACETATE is used as a key intermediate in the synthesis of various drug molecules. Its reactivity and functional groups make it suitable for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
METHYL 2-CYANO-2-(2-NITROPHENYL)ACETATE is also used in the agrochemical industry as a precursor for the synthesis of various pesticides and insecticides. Its unique properties enable the development of new agrochemicals with improved efficacy and selectivity.
Used in Specialty Chemicals:
In the specialty chemicals sector, METHYL 2-CYANO-2-(2-NITROPHENYL)ACETATE is used as a raw material for the production of various specialty chemicals, such as dyes, pigments, and polymers. Its versatility and reactivity contribute to the development of innovative products with unique properties and applications.

InChI:InChI=1/C10H8N2O4/c1-16-10(13)8(6-11)7-4-2-3-5-9(7)12(14)15/h2-5,8H,1H3

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 105-34-0 methyl 2-cyanoacetate 
• 1643377-91-6 methyl 2-fluoro-2-(2-nitrophenyl)acetate 
• 75-05-8 acetonitrile 

Downstream Products

• 113772-14-8 methyl 2-amino-1H-indole-3-carboxylate 
• 614755-48-5 2-cyano-2-(2-nitro-phenyl)-pent-4-enoic acid methyl ester 
• 724706-20-1 4-ethyl 1-methyl 2-cyano-2-(2-nitrophenyl)succinate 
• 67282-55-7 1-methoxy-1H-indole-3-carbaldehyde 
• 113772-15-9 methyl 2-amino-1-methylindole-3-carboxylate 
• 5719-08-4 4-chloro-1H-pyrimido[4,5-b]indole 

Relevant academic research and scientific papers

TfOH-Promoted Decyanative Cyclization toward the Synthesis of 2,1-Benzisoxazoles

A novel solvent-free, TfOH-promoted decyanative cyclization approach for the synthesis of 2,1-benzisoxazoles has been developed. The reactions are complete instantly at room temperature and result in the formation of the desired 2,1-benzisoxazoles in a 34-97% isolated yield.

COMPOUNDS AND METHODS

Disclosed are compounds having formula (I), wherein R1, R2, R3, R4, Z1, Z2, Z3 and Z4 are as defined herein, and methods of making and using the same.

Efficient total syntheses of phytoalexin and (±)-paniculidine B and C based on the novel methodology for the preparation of 1-methoxyindoles

A general route to 2-unsubstituted-1-methoxyindoles, based on our methodology for the synthesis of 1-methoxyindoles, is reported. This synthesis renders accessibility to a variety of natural products possessing the said skeleton. A direct synthesis of phy

An efficient total synthesis of 9-methoxycarbazole-3-carbaldehyde based on a novel methodology for the preparation of methoxyindoles

A direct synthesis of naturally occurring 9-methoxycarbazole-3-carbaldehyde 1, based on our methodology for the synthesis of 1-methoxyindoles, is reported. A novel benzannulation strategy was employed using ring closing metathesis as the key step in this total synthesis. The synthesis of the natural product 1 has been achieved in seven steps in 14% overall yield from commercial materials and in only four steps from a methoxyindole compound obtained using the new methodology.

Syntheses of Functionalised Pyridoindoles

Two complementary routes for the synthesis of highly functionalised pyridoindoles are described, starting from the readily available 2-amino-3-cyano-1-(4-methoxybenzyl)tetrahydroindole and methyl 2-aminoindole-3-carboxylate, respectively.The use of