113964-89-9

Upstream product

• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 113964-90-2 1-(3-isopropoxy-4-methoxyphenyl)ethanol 
• 88114-46-9 2-(3,4-dimethoxyphenyl)-4-(3-isopropoxy-4-methoxyphenyl)-4-oxobutyronitrile 
• 88114-45-8 3'-isopropoxy-3,4,4'-trimethoxychalcone 
• 88114-44-7 1-(3-isopropoxy-4-methoxyphenyl)-ethanone 
• 621-59-0 isovanillin 
• 154490-51-4 4-(3'-benzyloxy-4'-methoxy)phenyl-2-(3,4-dimethoxyphenyl)-4-oxobutyronitrile 
• 154490-50-3 3'-benzyloxy-3,4,4'-trimethoxy-chalcone 
• 154490-49-0 1-(3-benzyloxy-4-methoxyphenyl)ethanol 
• 23428-77-5 1‐(3‐(benzyloxy)‐4‐methoxyphenyl)ethanone 
• 154490-54-7 2-(3,4-dimethoxyphenyl)-4-(3'-hydroxy-4'-methoxy)phenyl butyric acid 
• 75-26-3 isopropyl bromide 
• 88114-47-0 2-(3,4-dimethoxyphenyl)-4-(3-isopropoxy-4-methoxyphenyl)-4-oxobutyric acid 

Downstream Products

• 88114-53-8 cis-2-(3,4-dimethylphenyl)-6-isopropoxy-7-methoxy-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine 
• 88114-56-1 cis-2-(3,4-dimethoxyphenyl)-6-isopropoxy-7-methoxy-1-(N-methyl-formamido)-1,2,3,4-tetrahydronaphthalene 
• 88114-54-9 2-(3,4-dimethoxyphenyl)-6-isopropoxy-7-methoxy-1-(N-methylformamido)naphthalene 
• 88114-52-7 [2-(3,4-Dimethoxy-phenyl)-6-isopropoxy-7-methoxy-3,4-dihydro-2H-naphthalen-(1Z)-ylidene]-methyl-amine 
• 88114-55-0 2-(3,4-dimethoxyphenyl)-6-hydroxy-7-methoxy-1-(N-methylformamido)naphthalene 
• 52259-64-0 fagaronine 
• 113964-91-3 2-(3,4-dimethoxyphenyl)-6-isopropyloxy-7-methoxy-3,4-dihydronaphthalen-1(2H)-one 
• 88114-51-6 2-(3,4-dimethoxyphenyl)-6-hydroxy-7-methoxy-3,4-dihydronaphthalen-1(2H)-one 

Relevant academic research and scientific papers

A formal new access to the benzo[c]phenanthridine alkaloids, synthesis of Nitidine and O-Methyl Fagaronine analogues

Previously unreported 2-aryl-1-naphthylamines were obtained in good yields from 2-aryl-1-tetraloneoximes by using the Semmler-Wolf reaction but omitting the acetic anhydride usually present in the reaction mixture. From these amines, through the thermal cyclization of their corresponding ethyl carbamates, a new access to the benzo[c]phenanthridin-6(5H)-ones was found. Preparation of water-soluble Nitidine and O-Methyl Fagaronine analogues bearing an alkylamino side chain on the C-6 position was achieved from these compounds.

Studies on the Chemical Constituents of Rutaceous Plants. Part 62. Efficient Synthesis of Fagaronine, a Phenolic Benzophenanthridine Alkaloid with Antileukaemic Activity

Fagarinone (2), an antileukaemic hydroxybenzophenanthridine alkaloid, has been synthesized from the chalcone (4a) according to the synthetic sequence (Schemes 1-4).During the synthesis, the hydroxy group was protected in the form of its isopropoxy deri