114-63-6

Basic information

• Product Name: Sodium 4-hydroxybenzoate
• Synonyms: Hydroxybenzoicsodiumsalt;SODIUM PARABEN;SODIUM HYDROXYBENZOATE;P-HYDROXYBENZOIC ACID SODIUM;4-HydroxybenzoicAcidSodiumSalt99+%Ultrapure;4-HYDROXYBENZOIC ACID NA SALT;4-HYDROXYBENZOIC ACID SODIUM SALT HPLC99+%;p-Hydroxybenzoic acid sodium salt, Sodium 4-hydroxybenzoate
• CAS NO: 114-63-6
• Molecular Formula: C₇H₅O₃*Na
• Molecular Weight: 160.1
• EINECS: 204-051-1
• Product Categories: Pharmaceutical Raw Materials;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 114-63-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 336.2 °C at 760 mmHg
• Flash Point: 171.3 °C
• Appearance: White to light beige/Crystalline Powder
• Vapor Pressure: 4.48E-05mmHg at 25°C
• Storage Temp.: Store at RT.
• Water Solubility: Soluble in water.
• BRN: 4163553
• CAS DataBase Reference: Sodium 4-hydroxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 4-hydroxybenzoate(114-63-6)
• EPA Substance Registry System: Sodium 4-hydroxybenzoate(114-63-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 2
• RTECS: DH2900000
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 114-63-6(Hazardous Substances Data)

Usage

Chemical Properties

White to light beige crystalline powder

Uses

It is used as a pharmaceutical intermediate.

Definition

ChEBI: An organic sodium salt resulting from the replacement of the proton from the carboxy group of 4-hydroxybenzoic acid by a sodium ion.

InChI:InChI=1/C7H6O3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

Upstream product

• 124-38-9 carbon dioxide 
• 139-02-6 sodium phenoxide 
• 532-32-1 sodium benzoate 

Downstream Products

• 76277-60-6 ethyl 3-bromo-2-ethoxy-2-(4-hydroxybenzoyloxy)propionate 
• 619-57-8 p-hydroxybenzamide 
• 94-18-8 Benzyl 4-hydroxybenzoate 
• 161620-19-5 [Cu(p-hydroxybenzoate)2(N,N-diethylnicotinamide)2] 
• 205055-88-5 [Cu(p-hydroxybenzoate)2(nicotinamide)2(H₂O)2] 
• 797760-17-9 [Ni(p-hydroxybenzoate)2(nicotinamide)2(H₂O)2] 
• 497072-32-9 [Cu(p-hydroxybenzoate)2(nicotinamide)2] 
• 130565-56-9 oxovanadium(IV) monochloro(4-hydroxybenzoate) 
• 1240242-86-7 tetraaqua(di-para-oxybanzoato)iron(II) tetrahydrate 

Related news

Regular ArticleEvaluation of Sodium 4-hydroxybenzoate (cas 114-63-6) as an Hydroxyl Radical Trap Using Gas Chromatography–Mass Spectrometry and High-Performance Liquid Chromatography with Electrochemical Detection08/30/2019

Molecular and tissue damage induced by reactive oxygen species is a serious consequence of the production of free radicals in biological systems. Biological markers produced by reactions with hydroxyl radicals are useful indices of free radical processesin vivo.In this respect, hydroxylation of ...detailed

Esterification of Sodium 4-hydroxybenzoate (cas 114-63-6) by ultrasound-assisted solid–liquid phase-transfer catalysis using dual-site phase-transfer catalyst08/23/2019

The catalytic esterification of sodium 4-hydroxybenzoate with benzyl bromide by ultrasound-assisted solid–liquid phase-transfer catalysis (U-SLPTC) was investigated using the novel dual-site phase-transfer catalyst 4,4′-bis(tributylammoniomethyl)-1,1′-biphenyl dichloride (BTBAMBC), which was ...detailed

Relevant articles and documents

The improved Kolbe-Schmitt reaction using supercritical carbon dioxide

A comparative analysis of the reactions between sodium phenoxide and CO2 under the gaseous and supercritical conditions has demonstrated the preferential effect of supercritical conditions for promoting the reactivity of CO2. A significant increase in product yield was obtained in supercritical CO2 compared to reactions undertaken in gaseous CO2.

Effect of Polyether Linkages on the Carboxylation of Sodium Phenoxide

In the carboxylation of sodium phenoxide under mild conditions, the crown compound or polyethers with three to five ether linkages caused carboxylation to give o- and p-hydroxybenzoic acids, but not ethers with one or two linkages.The chelation of sodium phenoxide with polyethers changed the formation ratio of isomers.