1140-17-6

Basic information

• Product Name: 2-AMINO-4'-BROMOBENZOPHENONE
• Synonyms: (2-AMINO-PHENYL)-(4-BROMO-PHENYL)-METHANONE;Methanone,(2-aMinophenyl)(4-broMophenyl)-;-bromobenzophenone
• CAS NO: 1140-17-6
• Molecular Formula: C₁₃H₁₀BrNO
• Molecular Weight: 276.13
• Product Categories: Aromatic Benzophenones & Derivatives (substituted)
• Mol File: 1140-17-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 103-110 °C
• Boiling Point: 432.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.484±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.36±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4'-BROMOBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4'-BROMOBENZOPHENONE(1140-17-6)
• EPA Substance Registry System: 2-AMINO-4'-BROMOBENZOPHENONE(1140-17-6)

Safety Data

• Hazard Codes: Xi,N
• Statements: 43-51/53
• Safety Statements: 36/37-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 1140-17-6(Hazardous Substances Data)

Usage

General Description

2-AMINO-4'-BROMOBENZOPHENONE, also known as 4'-Bromo-2-aminobenzophenone, is a chemical compound with the molecular formula C13H10BrNO. It is a benzophenone derivative with a bromine atom at the 4' position and an amino group at the 2 position. 2-AMINO-4'-BROMOBENZOPHENONE is commonly used as a photoinitiator in the production of light-curable materials like adhesives, inks, coatings, and dental composites. It also has potential applications in the field of organic electronics and pharmaceuticals. However, its use may be restricted and regulated due to its potential toxicity and environmental impacts.

Upstream product

• 118667-16-6 4-bromo-benzophenone-(E)-oxime 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 589-87-7 1,4-bromoiodobenzene 
• 861781-61-5 (2-nitrophenyl)(4-bromophenyl)methanone 
• 34176-08-4 sodium 4-bromobenzenesulfinate 
• 1885-29-6 anthranilic acid nitrile 
• 5467-74-3 4-Bromophenylboronic acid 
• 106-37-6 1.4-dibromobenzene 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 118-48-9 isatoic anhydride 
• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 51012-29-4 2-((4-bromophenyl)sulfonamido)benzoic acid 
• 118-92-3 anthranilic acid 
• 941-55-9 4-toluenesulfonyl azide 

Downstream Products

• 500870-79-1 2-N-(4-methylsulfonylbenzoyl)-amide-4'-bromo-benzophenone 
• 1010690-99-9 syn-(2-aminophenyl)(4-bromophenyl)methanone oxime 
• 1332696-79-3 4-(para-bromo)phenylquinazoline 
• 1315477-66-7 3-(4-bromophenyl)-1-tosyl-1H-indole-2-carbaldehyde 
• 1315477-47-4 1-(4-bromophenyl)-1-(2-(tosylamino)phenyl)prop-2-yn-1-ol 
• 1381805-49-7 4,4',4''-tris(4-bromophenylquinolin-2-yl)triphenylamine 
• 1374862-46-0 (2-aminophenyl)(4'-methoxy-[1,1'-biphenyl]-4-yl)methanone 
• 1374862-47-1 (2-aminophenyl)(4'-(tert-butyl)-[1,1'-biphenyl]-4-yl)methanone 
• 1610460-76-8 3-benzyl-3-(4-bromophenyl)-1-methylindolin-2-one 

Relevant articles and documents

Palladium-catalyzed direct addition of 2-Aminobenzonitriles to sodium arylsulfinates: Synthesis of o-Aminobenzophenones

The first example of the palladium-catalyzed synthesis of o-Aminobenzophenones in moderate to excellent yields via a direct addition of sodium arylsulfinates to unprotected 2-Aminobenzonitriles was reported. A plausible mechanism for the formation of o-Aminobenzophenones involving desulfination and addition reactions was proposed. The utility of this transformation was demonstrated by its compatibility with a wide range of functional groups. Thus, the method represents a convenient and practical strategy for synthesis of o-Aminobenzophenones.

Benzene type liquid crystal compound and preparation method thereof

The invention relates to the technical field of liquid crystal compounds, in particular to a benzene liquid crystal compound and a preparation method thereof, wherein the benzene type liquid crystal compound is N. 4 , N4 , N4 ’ , N4 ’ - (9, 9 - Diphenyl - 9H - fluorene -3 - yl) -2 - methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine, the preparation method of the benzene type liquid crystal compound is that 2 - nitrobenzoic acid is used as a starting material to react with oxalyl chloride to obtain 2 - nitrobenzoyl chloride. The reaction was again reacted with bromobenzene to give (4 - bromophenyl) (2 - nitrophenyl) methyl ketone. The reduction reaction is followed by obtaining (4 - bromophenyl) (2 - aminophenyl) methyl ketone. The 3 - bromo - 9H - fluorene -9 - ketone is obtained by using sulfuric acid and sodium nitrite as a catalyst. The Grignard reagent of bromobenzene is reacted again to obtain 3 - bromo -9, 9 - diphenyl - 9H - fluorene. Reaction with cuprous iodide gives 3 - iodine -9, 9 - diphenyl - 9H - fluorene. 2 - Methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine was prepared, and then reacted with 3 - iodine -9, 9 - diphenyl - 9H - fluorene to obtain the benzene-based liquid crystal compound of the present invention. The invention can be applied to preparation of liquid crystal mixtures, liquid crystal display device materials or electro-optical display device materials.

One-Pot Synthesis of Spirocyclopenta[ a]indene Derivatives via a Cascade Ring Expansion and Intramolecular Friedel-Crafts-Type Cyclization

A one-pot efficient synthetic approach for the rapid construction of spirocyclopenta[a]indene derivatives has been developed via an iodine-initiated cascade ring expansion and intramolecular Friedel-Crafts-type cyclization from propargyl alcohol-tethered alkylidenecyclobutanes under mild conditions with broad substrate scope. This cascade process can be elegantly conducted on a gram scale. A plausible reaction mechanism has been proposed on the basis of a series of deuterium labeling and control experiments.

Gold-catalyzed cyclization of 1-(2′-Azidoaryl) propynols: Synthesis of polysubstituted 4-quinolones

An unprecedented gold-catalyzed procedure for the synthesis of polysubstituted 4-quinolones from 1-(2′-Azidoaryl) propynols is described. The reaction undergoes an intramolecular nucleophilic attack of the azide group to the Au-Activated triple bonds in a 6-endo-dig manner and subsequent gold-Assisted expulsion of N2 to furnish an α-imino gold carbene intermediate, which triggers a 1,2-carbon migration and finally is converted to 2,3-disubstituted 4-quinolone.