114414-17-4 Usage
General Description
2-Amino-3-hydroxy-4-bromopyridine HBR is a chemical compound with the molecular formula C5H6BrN2O and a molecular weight of 211.02 g/mol. It is a derivative of pyridine and contains a bromine atom, an amino group, and a hydroxy group. 2-AMINO-3-HYDROXY-4-BROMOPYRIDINE HBR can be used for various purposes, including in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a building block in the production of functional materials and in research and development. Additionally, 2-Amino-3-hydroxy-4-bromopyridine HBR may have potential biological and pharmacological activities, making it of interest for further study in the fields of medicine and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 114414-17-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,1 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 114414-17:
(8*1)+(7*1)+(6*4)+(5*4)+(4*1)+(3*4)+(2*1)+(1*7)=84
84 % 10 = 4
So 114414-17-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrN2O.BrH/c6-3-1-2-8-5(7)4(3)9;/h1-2,9H,(H2,7,8);1H
114414-17-4Relevant articles and documents
POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES
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Page/Page column 154, (2021/01/29)
The current invention provides urea derivatives, in particular compounds having the core structure heteroaryl-NH-CO-NH-aryl-O- heteroaryl, for use in treating, ameliorating, delaying, curing and/ or preventing a disease or condition associated with muscle cells and/or satellite cells, such as Duchenne muscular dystrophy, Becker muscular dystrophy, cachexia or sarcopenia.
NOVEL INHIBITORS OF MAP4K1
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Page/Page column 53, (2018/12/13)
The invention relates to novel inhibitors of MAP4K1 (HPK1) useful for the treatment of diseases or disorders characterised by dysregulation of the signal transduction pathways associated with MAPK activation, including hyperproliferative diseases, diseases of immune system dysfunction, inflammatory disorders, neurological diseases, and cardiovascular diseases. The invention further relates to pharmaceutical compositions comprising the same and methods of treatment of said diseases and disorders. The inhibitors are of formula (I) wherein the definitions for A, D, E, F, R5, R6, R7, Z, ring Q, n, x and y are as given in the application.