114419-08-8

Basic information

• Product Name: D-myo-Inositol, 2,4,5-tris-O-(phenylmethyl)-
• Synonyms: D-myo-Inositol, 2,4,5-tris-O-(phenylmethyl)-
• CAS NO: 114419-08-8
• Molecular Formula: C₂₇H₃₀O₆
• Molecular Weight: 450.52
• Mol File: 114419-08-8.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• CAS DataBase Reference: D-myo-Inositol, 2,4,5-tris-O-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: D-myo-Inositol, 2,4,5-tris-O-(phenylmethyl)-(114419-08-8)
• EPA Substance Registry System: D-myo-Inositol, 2,4,5-tris-O-(phenylmethyl)-(114419-08-8)

Safety Data

• Hazardous Substances Data: 114419-08-8(Hazardous Substances Data)

Upstream product

• 111392-18-8 (+/-)-1,3,4-tri-O-allyl-5,6-di-O-benzyl-myo-inositol 
• 100-39-0 benzyl bromide 
• 161972-49-2 (-)-1L-2,5,6-tri-O-benzyl-3-O-(p-methoxybenzyl)-myo-inositol 
• 98906-32-2 (±)-1,4-di-O-allyl-2,3:5,6-di-O-isopropylidene-myo-inositol 
• 115072-72-5 2,3,6-tri-O-benzyl-4,5-isopropylidene-1-O-(prop-1-enyl)-myo-inositol 
• 115072-72-5 (3aR,4S,5R,6R,7S,7aR)-4,5,7-Tris-benzyloxy-2,2-dimethyl-6-[((E)-propenyl)oxy]-hexahydro-benzo[1,3]dioxole 
• 114218-16-5 1-O-allyl-2,3,6-tri-O-benzyl-myo-inositol 
• 129662-38-0 C₃₉H₅₄O₁₂ 
• 111408-68-5 3,6-di-O-benzyl-D/L-myo-inositol 
• 108-05-4 vinyl acetate 
• 501669-17-6 (±)-1,3,6-tri-O-benzyl-myo-inositol 
• 162991-32-4 (1R,2R,3S,4R,5R,6R)-4,5-Bis-benzyloxy-3,6-bis-(4-methoxy-benzyloxy)-cyclohexane-1,2-diol 
• 162879-71-2 bis-(-)-ω-camphonate of 1,6-di-O-benzyl-2,5-di-O-p-methoxybenzyl-myo-inositol 
• 162991-39-1 (3aR,4R,5S,6S,7R,7aS)-4,7-Bis-benzyloxy-5,6-bis-[((E)-but-2-enyl)oxy]-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 

Downstream Products

• 115510-57-1 D-1,3,6-tri-O-benzyl-2,4,5-tris-O-[di(benzyloxy)phosphoryl]-myo-inositol 
• 114342-70-0 Phosphoric acid dibenzyl ester (1R,2R,3R,4R,5R,6S)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyl ester 
• 114342-70-0 Phosphoric acid dibenzyl ester (1R,2R,3S,4R,5R,6S)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyl ester 
• 114342-70-0 DL-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol 
• 114419-09-9 (-)-1L-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol 
• 104826-14-4 (+/-)-1,2,4-tri-O-benzyl-3,5,6-tris-O-dianilinophosphoryl-myo-inositol 
• 162991-62-0 (3aR,4S,5S,6R,7S,7aR)-4,6,7-Tris-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-5-ol 
• 196302-88-2 1D-2,4,5-tri-O-benzyl-1-O-endo,6-O-exo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,4,5-tri-O-benzyl-1-O-exo,6-O-endo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,5,6-tri-O-benzyl-3-O-exo,4-O-endo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,5,6-tri-O-benzyl-3-O-endo,4-O-exo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 92216-45-0 D-myo-inositol 2,4,5-trisphosphate 
• 501921-39-7 D-1,3,6-tri-O-benzyl-2,4,5-tris-O-[di(benzyloxy)thiophosphoryl]-myo-inositol 
• 226889-48-1 (1S,2S,3R,4S,5S,6S)-3,4,6-Tris-benzyloxy-5-(4-methoxy-benzyloxy)-cyclohexane-1,2-diol 

Relevant articles and documents

Synthesis and in vitro anticancer activity evaluation of novel bioreversible phosphate inositol derivatives

The chemistry and biology of phosphorylated inositols have become intense areas of research during the last two decades due to their involvement in various cellular signaling processes. However, the metabolic instability by phosphatases or kinases and poo

Kinetic resolution of a precursor for myo-inositol phosphates under continuous flow conditions

In this work, we have investigated the biocatalytic continuous flow process with a packed-bed reactor for the kinetic resolution of (±)-1,3,6-tri-O- benzyl-myo-inositol ((±)-1) by alcoholysis using Novozym 435. Excellent conversions and stereselectivities were attained in short reaction time. We found that this enzymatic transformation under continuous flow in TBME with vinyl acetate (10:1 ratio with (±)-1) at 50°C, with a 3 min-residence time secured the best results (50% conversion and eep > 99%). The feasibility of a continuous operation of the Novozym 435-containing-packed-bed reactor over a longer period of time was demonstrated via a 9-cycle experiment wherein the lipase remained stable.

Kinetic resolution of 1,3,6-tri-O-benzyl-myo-inositol by Novozym 435: Optimization and enzyme reuse

myo-Inositol derivatives bearing selectively protected hydroxyl groups are relevant precursors of high-value myo-inositols. In the present study, we applied the response surface method to the optimization of kinetic resolution of (±)-1,3,6-tri-O-benzyl-my