1145-55-7

Usage

Uses

Used in Perfumery and Flavoring Industry:
Tert-butyl (2Z)-2-cyano-3-phenylprop-2-enoate is used as a fragrance ingredient and flavoring agent for its slightly fruity odor. It contributes to the creation of various scents and tastes in perfumes and food products, enhancing their overall appeal and sensory experience.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, tert-butyl (2Z)-2-cyano-3-phenylprop-2-enoate serves as a precursor in the synthesis of various drugs. Its unique chemical structure allows for the development of new medicinal compounds with potential therapeutic applications.
Used in Agricultural Chemicals:
Tert-butyl (2Z)-2-cyano-3-phenylprop-2-enoate is also utilized as a starting material in the production of agricultural chemicals. Its chemical properties make it suitable for the synthesis of pesticides, herbicides, and other agrochemicals that help protect crops and enhance agricultural productivity.

Upstream product

• 1116-98-9 cyanoacetic acid tert-butyl ester 
• 100-52-7 benzaldehyde 

Downstream Products

• 75391-14-9 2-Cyan-3-phenyl-3-(1-pyrrolyl)propionsaeure-tert-butylester 
• 75140-69-1 C₂₀H₂₁NO₂ 
• 75391-17-2 3-phenyl-3-(1H-pyrrol-1-yl)propanoic acid 
• 75391-21-8 1-Amino-3-phenyl-3H-pyrrolizin-2-carbonsaeure-tert-butylester 

Relevant academic research and scientific papers

High catalytic activity of as-synthesized, ordered porous silicate-quaternary ammonium composite for Knoevenagel condensation

The Knoevenagel condensation of carbonyl compounds with active methylene compounds catalyzed by as-synthesized, ordered porous silicate-quaternary ammonium composite materials gave corresponding α,β-unsaturated esters in high yields under very mild liquid phase conditions.

Synthesis of Metallomacrocycle and Coordination Polymers with Pyridine-Based Amidocarboxylate Ligands and Their Catalytic Activities towards the Henry and Knoevenagel Reactions

The reactions of 3,3′-{(pyridine-2,6-dicarbonyl)bis(azanediyl)}dibenzoic acid (H2L) with zinc(II), cadmium(II), and samarium(III) nitrates were studied, and the obtained compounds, [Zn(1κO:2κO′-L)(H2O)2]n (1), [

Three-dimensional porous coordination polymer functionalized with amide groups based on tridentate ligand: Selective sorption and catalysis

To create a functionalized porous compound, amide group is used in porous framework to produce attractive interactions with guest molecules. To avoid hydrogen-bond formation between these amide groups our strategy was to build a three-dimensional (3D) coo

One-Pot Synthesis of γ-Azidobutyronitriles and Their Intramolecular Cycloadditions

Efficient gram-scale, one-pot approaches to azidocyanobutyrates and their amidated or decarboxylated derivatives have been developed, starting from commercially available aldehydes and cyanoacetates. These techniques combine (1) Knoevenagel condensation,

Amine-grafted on lanthanide metal-organic frameworks: Three solid base catalysts for Knoevenagel condensation reaction

A post-synthetic modification strategy has been used to prepare three solid base catalysts, including Er(btc)(ED)0.75(H2O)0.25 (2, btc = 1,3,5-benzenetricarboxylates, ED = 1,2-ethanediamine), Er(btc)(PP)0.55(Hs

A metal-organic framework gel with Cd2+ derived from only coordination bonds without intermolecular interactions and its catalytic ability

A cyclohexane-based ligand (1) as a triconnected linker forms a supramolecular gel in the presence of transition metal ions, particularly Cd2+ and Zn2+. 1 can also be gelated with cadmium counter ions such as NO3-/su

Copper-catalyzed 1,4-addition of organoboronates to alkylidene cyanoacetates: Mechanistic insight and application to asymmetric catalysis

In addition: A copper/N-heterocyclic carbene(NHC)-catalyzed 1,4-addition of organoboronates to alkylidene cyanoacetates was developed, in which the catalytic cycle is proposed to consist of a transmetalation/insertion/ligand exchange. An effective asymmetric variant has also been achieved by the use of a chiral NHC ligand (see scheme). Copyright