Cas 1146952-01-3,5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine

1146952-01-3

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Basic information

Product Name: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine
CAS NO:1146952-01-3
Molecular Formula:
Molecular Weight: 867.376
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine(CAS DataBase Reference)
NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine(1146952-01-3)
EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidite)-2'-O-[1-(2-chloroethoxy)ethyl]-2'-C-methyluridine(1146952-01-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1146952-01-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1146952-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,9,5 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1146952-01:
(9*1)+(8*1)+(7*4)+(6*6)+(5*9)+(4*5)+(3*2)+(2*0)+(1*1)=153
153 % 10 = 3
So 1146952-01-3 is a valid CAS Registry Number.

1146952-01-3Upstream product

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1146952-01-3Relevant academic research and scientific papers

2-C-Methyluridine modified hammerhead ribozyme against the estrogen receptor

Pontiggia, Rodrigo,Pontiggia, Osvaldo,Simian, Marina,Montserrat, Javier M.,Engels, Joachim W.,Iribarren, Adolfo M.

, p. 2806 - 2808 (2010)

A new synthesis of 2′-C-methyluridine phosphoramidite is presented. Special emphasis is dedicated to the improvement of the protection of the tertiary 2′-hydroxyl group. Comparison to previous protecting strategies and analysis of stability under 5′-DMTr removing conditions are discussed. The synthetic incorporation of this modified nucleoside into the catalytic core of a hammerhead ribozyme against the estrogen receptor α protein (ER-α), and transfection experiments in MCF-7 cell line are also presented.

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