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114744-51-3

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114744-51-3 Usage

General Description

7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE is a chemical compound with the molecular formula C9H10BrN?HCl. It is a synthetic quinoline derivative that is used primarily in the research and development of pharmaceuticals, particularly in the field of anti-inflammatory and analgesic drugs. The compound is typically used as an intermediate in the synthesis of various pharmaceuticals due to its potential to modulate biological pathways and target specific receptors in the body. It is important to handle this compound with caution, as it may have potential hazards and safety considerations that need to be carefully assessed and managed.

Check Digit Verification of cas no

The CAS Registry Mumber 114744-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,7,4 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 114744-51:
(8*1)+(7*1)+(6*4)+(5*7)+(4*4)+(3*4)+(2*5)+(1*1)=113
113 % 10 = 3
So 114744-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10BrN.ClH/c10-8-4-3-7-2-1-5-11-9(7)6-8;/h3-4,6,11H,1-2,5H2;1H

114744-51-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Bromo-1,2,3,4-tetrahydroquinoline

1.2 Other means of identification

Product number -
Other names 7-bromo-1,2,3,4-tetrahydroquinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:114744-51-3 SDS

114744-51-3Relevant articles and documents

Encapsulating Cobalt into N-Doping Hollow Frameworks for Efficient Cascade Catalysis

Yun, Ruirui,Zhang, Beibei,Qiu, Chuang,Ma, Ziwei,Zhan, Feiyang,Sheng, Tian,Zheng, Baishu

, p. 9757 - 9761 (2021)

The development of nonprecious catalysts for hydrogenation of organic molecules is of great importance in heterogeneous catalysis. Herein, we report a series of N-doped hollow carbon frameworks encompassing cobalt nanoparticles (denoted as Co@NHF-900) constructed as a new kind of reusable catalyst for this purpose by pyrolysis of ZIF-8@Co-dopamine under Ar atmospheres. Notably, the framework of ZIF-8 is essential for efficient catalyst by providing a carbon framework to support Co-dopamine. The experimental results reveal that the ZIF-8 renders a large hollow place within the catalysts, allowing the enrichment of the substrate and windows of the hollow structure and the ease of mass transfer of products during the reaction. All of the virtues made Co@NHF-900 a good candidate for hydrogenation of quinolines with high activity (TOF value of 119 h-1, which is several times than that of akin catalysts) and chemoselectivity.

Cu Nanoclusters Anchored on the Metal-Organic Framework for the Hydrolysis of Ammonia Borane and the Reduction of Quinolines

Yun, Ruirui,Zhang, Beibei,Zhan, Feiyang,Du, Liting,Wang, Zhaoxu,Zheng, Baishu

supporting information, p. 12906 - 12911 (2021/08/30)

Free-access active sites created and the interaction regulated between them and substrates during the heterogeneous catalysis process are crucial, which remain a great challenge. In this work, in suit reduced to afford naked Cu nanoparticles (NPs) have been anchored on the metal-organic framework (MOF), NH2-MOF, to form Cu-NH2-MOF. The strategy can precisely control the Cu NP formation with small size and uniform distribution. The Cu NP properties and MOF advantages have been integrated to create a great catalyst with multiple functions and have resulted in improving the recyclability and superb catalytic activity for the one-pot reduction of heterocycle reactions under mild conditions. The experimental and theoretical calculation results show that the superior performance should be attributed to the framework of NH2-MOF that provides large caves for substrate enrichment and the stabilization of Cu sites by the -NH2 group.

Structure-guided rescaffolding of selective antagonists of BCL-X L

Koehler, Michael F. T.,Bergeron, Philippe,Choo, Edna F.,Lau, Kevin,Ndubaku, Chudi,Dudley, Danette,Gibbons, Paul,Sleebs, Brad E.,Rye, Carl S.,Nikolakopoulos, George,Bui, Chinh,Kulasegaram, Sanji,Kersten, Wilhelmus J. A.,Smith, Brian J.,Czabotar, Peter E.,Colman, Peter M.,Huang, David C. S.,Baell, Jonathan B.,Watson, Keith G.,Hasvold, Lisa,Tao, Zhi-Fu,Wang, Le,Souers, Andrew J.,Elmore, Steven W.,Flygare, John A.,Fairbrother, Wayne J.,Lessene, Guillaume

supporting information, p. 662 - 667 (2014/07/07)

Because of the promise of BCL-2 antagonists in combating chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL), interest in additional selective antagonists of antiapoptotic proteins has grown. Beginning with a series of selective, potent BC

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