1493774-32-5

Basic information

• Product Name: 4-bromo-2-nitro-benzenepropanoic acid methyl ester
• Synonyms: 4-bromo-2-nitro-benzenepropanoic acid methyl ester
• CAS NO: 1493774-32-5
• Molecular Weight: 288.098
• Mol File: 1493774-32-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-nitro-benzenepropanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-nitro-benzenepropanoic acid methyl ester(1493774-32-5)
• EPA Substance Registry System: 4-bromo-2-nitro-benzenepropanoic acid methyl ester(1493774-32-5)

Safety Data

• Hazardous Substances Data: 1493774-32-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 114744-51-3 7-bromo-1,2,3,4-tetrahydroquinoline 
• 577-19-5 2-nitrophenyl bromide 
• 39228-29-0 methyl 2-nitrocinnamate 
• 1664-65-9 3-(2-nitrophenyl)propionic acid methyl ester 

Relevant articles and documents

Deconstructive di-functionalization of unstrained, benzo cyclic amines by C-N bond cleavage using a recyclable tungsten catalyst

With H2WO4 as the catalyst and H2O2 as the oxidant, we herein report a deconstructive difunctionalization of the C-N bond in unstrained, benzo cyclic amines to generate an ester group and nitro group simultaneously. The preliminary mechanistic studies suggested that the corresponding hydroxamic acid is the key intermediate for this transformation. Importantly, with the utilization of this transformation, we achieved an interesting approach for the ring contraction of quinoline to indole, an example of scaffold hopping in a hetero-aromatic system.