114745-45-8

Basic information

• Product Name: CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER
• Synonyms: CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER;Ethyl cis-2-AMinocyclopentanecarboxylate;(1R,2S)-ethyl 2-aminocyclopentanecarboxylate
• CAS NO: 114745-45-8
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.21
• Mol File: 114745-45-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 213.4°C at 760 mmHg
• Flash Point: 82.5°C
• Appearance: /
• Density: 1.045g/cm³
• Vapor Pressure: 0.164mmHg at 25°C
• Refractive Index: 1.473
• CAS DataBase Reference: CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER(114745-45-8)
• EPA Substance Registry System: CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER(114745-45-8)

Safety Data

• Hazardous Substances Data: 114745-45-8(Hazardous Substances Data)

Usage

General Description

CIS-2-Amino-cyclopentanecarboxylic acid ethyl ester is a chemical compound with the molecular formula C8H15NO2. It is an ester derivative of cis-2-amino-cyclopentanecarboxylic acid, which is a cyclic amino acid. CIS-2-AMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER is used in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development. It is also used in the production of peptides and other bioactive compounds. The ethyl ester form of the compound allows for easier handling and manipulation in chemical reactions.

InChI:InChI=1/C8H15NO2/c1-2-11-8(10)6-4-3-5-7(6)9/h6-7H,2-5,9H2,1H3/t6-,7+/m1/s1

Upstream product

• 1033755-97-3 2-benzylamino-cyclopentanecarboxylic acid ethyl ester 
• 64-17-5 ethanol 
• 22031-52-3 cis-2-aza-3-oxobicyclo<3.2.0>heptane 
• 142-29-0 cyclopentene 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 7149-18-0 ethyl 2-amino-1-cyclopentene-1-carboxylate 

Downstream Products

• 197916-36-2 ethyl (1R,2S)-2-aminocyclopentane-1-carboxylate 
• 311341-94-3 ethyl trans-2-isothiocyanato-1-cyclopentanecarboxylate 
• 311341-94-3 ethyl cis-2-isothiocyanato-1-cyclopentanecarboxylate 
• 141045-77-4 Ethyl trans-2-(N-Benzylamino)cyclopentanecarboxylate 
• 158262-07-8 ethyl cis-2-benzylamino-1-cyclopentanecarboxylate 
• 128668-89-3 cis-3-phenyl-1,2,3,4a,5,6,7,7a-octahydrocyclopentapyrimidine-2,4-dione 
• 135053-11-1 trans-2-aminocyclopentanecarboxamide 

Relevant articles and documents

SUBSTITUTED PYRROLO-PYRIDINONE DERIVATIVES AND THERAPEUTIC USES THEREOF

Compounds of formula (I), processes for their production and their use as pharmaceuticals.

Dirhodium(II)-Catalyzed (3 + 2) Cycloaddition of the N-Arylaminocyclopropane with Alkene Derivatives

Several (3 + 2) cycloaddition reactions catalyzed by dirhodium(II) complexes between N-arylaminocyclopropane and alkenes derivative have been developed. Preliminary mechanism studies suggest that dirhodium(II) complexes may decrease the bond-dissociation

Expanding dynamic kinetic protocols: Transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives

Several α-alkylated β-amino esters have been obtained via DKR processes employing a kit of transaminases and isopropylamine as an amino donor in aqueous medium under mild conditions. Thus, while acyclic α-alkyl-β-keto esters afforded excellent conversions and enantioselectivities, although usually low diastereoselectivities, using more constrained cyclic β-keto esters high to excellent inductions were obtained.