114748-67-3

Basic information

• Product Name: 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine
• Synonyms: 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine;7-I-7-Deaza-ddG;2-Amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-4H-pyrrolo[2,3-d]pyrimidin-4-one;7-Iodo-2',3'-Dideoxy-7-Deaza-D-Guanosine;4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7-Deaza-2'3'-dideoxy-7-iodoguanosine
• CAS NO: 114748-67-3
• Molecular Formula: C11H13IN4O3
• Molecular Weight: 376.15
• EINECS: -0
• Mol File: 114748-67-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 2.35±0.1 g/cm3(Predicted)
• PKA: 10.28±0.20(Predicted)
• CAS DataBase Reference: 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine(114748-67-3)
• EPA Substance Registry System: 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine(114748-67-3)

Safety Data

• Hazardous Substances Data: 114748-67-3(Hazardous Substances Data)

Usage

General Description

7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine is a chemical compound with the molecular formula C10H12IN5O3. It is a modified nucleoside analog of guanosine, with a deaza or deoxyriboside sugar moiety and an iodo substituent at the 7 position. 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine has been studied for its potential antiviral activity, particularly against herpes simplex virus and human immunodeficiency virus (HIV). It is believed to inhibit viral replication by interfering with the synthesis of viral DNA. Because of its unique structure, 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine is also being investigated for its potential use in cancer therapy. Overall, this chemical compound shows promise for various therapeutic applications due to its distinct structure and potential antiviral and anticancer properties.

Upstream product

• 114748-66-2 2-Amino-5-iodo-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 98891-39-5 7-(2'-Desoxy-β-D-erythro-pentofuranosyl)-4-methoxy-2-methylthio-7H-pyrrolo<2,3-d>pyrimidin 
• 114748-63-9 4-Methoxy-2-methylsulfanyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 114748-62-8 (2R,3S,5R)-5-(4-Methoxy-2-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-trityloxymethyl-tetrahydro-furan-3-ol 
• 114748-65-1 5-Iodo-2-methylsulfanyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 114748-64-0 5-Iodo-4-methoxy-2-methylsulfanyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 29877-76-7 4-methoxy-2-methylthio-7H-pyrrolo[2,3-d]pyrimidine 
• 115899-60-0 5-Iodo-2-methanesulfinyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 115920-25-7 Thiocarbonic acid O-[(2R,3S,5R)-5-(4-methoxy-2-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl] ester O-phenyl ester 

Downstream Products

• 114748-68-4 N-{3-[2-Amino-7-((S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl]-prop-2-ynyl}-2,2,2-trifluoro-acetamide 
• 114748-68-4 N-{3-[2-Amino-4-hydroxy-7-((2R,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-prop-2-ynyl}-2,2,2-trifluoro-acetamide 
• 114748-68-4 N-{3-[2-Amino-7-((2R,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl]-prop-2-ynyl}-2,2,2-trifluoro-acetamide 

Relevant articles and documents

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