114748-63-9

Upstream product

• 114748-62-8 (2R,3S,5R)-5-(4-Methoxy-2-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-trityloxymethyl-tetrahydro-furan-3-ol 
• 115920-25-7 Thiocarbonic acid O-[(2R,3S,5R)-5-(4-methoxy-2-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl] ester O-phenyl ester 
• 29877-76-7 4-methoxy-2-methylthio-7H-pyrrolo[2,3-d]pyrimidine 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 76-83-5 trityl chloride 
• 98891-39-5 7-(2'-Desoxy-β-D-erythro-pentofuranosyl)-4-methoxy-2-methylthio-7H-pyrrolo<2,3-d>pyrimidin 

Downstream Products

• 114748-64-0 5-Iodo-4-methoxy-2-methylsulfanyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 115899-60-0 5-Iodo-2-methanesulfinyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 114748-68-4 N-{3-[2-Amino-7-((2R,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl]-prop-2-ynyl}-2,2,2-trifluoro-acetamide 
• 114748-65-1 5-Iodo-2-methylsulfanyl-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 114748-66-2 2-Amino-5-iodo-7-((2R,5S)-5-trityloxymethyl-tetrahydro-furan-2-yl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 114748-67-3 7-iodo-2',3'-dideoxy-7-deazaguanosine 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF 7-IODO-2',3'-DIDEOXY-7-DEAZAPURINE NUCLEOSIDES, KEY INTERMEDIATES IN THE PREPARATION OF REAGENTS FOR THE AUTOMATED SEQUENCING OF DNA

Practical synthesis of 7-iodo-2',3'-dideoxy-7-deazaadenosine and 7-iodo-2',3'-dideoxy-7-deazaguanosine are described.These iodonucleosides can be converted into fluorescence-tagged chain-terminating substrates for DNA polymerases.