1147713-98-1

Upstream product

• 100-39-0 benzyl bromide 
• 101969-75-9 (2-fluorophenyl)(4-hydroxyphenyl)methanone 

Downstream Products

• 1421854-27-4 1-(1-(4-(benzyloxy)phenyl)vinyl)-2-fluorobenzene 
• 1421854-18-3 4-(4,4-difluoro-1-(2-fluorophenyl)cyclohexyl)-2-fluorophenol 
• 1421854-17-2 1-(4,4-difluoro-1-(4-methoxyphenyl)cyclohexyl)-2-fluorobenzene 
• 1421854-33-2 4-(2-fluorophenyl)-4-(4-methoxyphenyl)cyclohexanone 
• 1421854-16-1 4-(4,4-difluoro-1-(2-fluorophenyl)cyclohexyl)phenol 
• 1421854-32-1 4-(4-(tert-butyldimethylsilyloxy)phenyl)-4-(2-fluorophenyl)cyclohexanone 
• 1421854-31-0 4-(2-fluorophenyl)-4-(4-hydroxyphenyl)cyclohexanone 
• 1421854-30-9 4-(4-(benzyloxy)phenyl)-4-(2-fluorophenyl)cyclohex-2-enone 
• 1421854-29-6 2-(4-(benzyloxy)phenyl)-2-(2-fluorophenyl)acetaldehyde 
• 1421854-28-5 2-(4-(benzyloxy)phenyl)-2-(2-fluorophenyl)ethanol 
• 1147714-07-5 1-((4-(benzyloxy)phenyl)(cyclohexylidene)methyl)-2-fluorobenzene 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES

The present application relates to a composition comprising a selective androgen modulating compound of formula (I) and selective estrogen receptor β agonist of formula (II). The present application also relates to the use of a selective androgen modulating compound of formula (I) in combination with a selective estrogen receptor β agonist of formula (II) in the treatment or prevention of neurodegenerative diseases or disorders,such as Alzheimer's disease, Huntigton's disease, Parkinson's disease, depression, anxiety, multiple sclerosis, symptoms associated with or caused by multiple sclerosis, and acute or chronic pain.

DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA

Disclosed herein are novel di-aromatic compounds of the general formula (I). Also pharmaceutical compositions comprising the novel compounds and the use of the novel compounds in treatment and prevention of diseases and disorders related to estrogen receptors are disclosed. Furthermore, methods for treating and preventing diseases and disorders related to estrogen receptors by administration of the novel compounds are disclosed.

Diphenyl substituted cyclohexane derivatives, useful as modulators of the estrogen receptors beta

Disclosed herein are novel di-aromatic compounds of the general formula (I): Also pharmaceutical compositions comprising the novel compounds and the use of the novel compounds in treatment and prevention of diseases and disorders related to estrogen receptors are disclosed. Furthermore, methods for treating and preventing diseases and disorders related to estrogen receptors by administration of the novel compounds are disclosed.

CONDENSED COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS

Disclosed herein are compounds of Formula (I) as disclosed herein, methods of modulating the activity of an estrogen receptor and methods of treating a disorder associated with estrogen receptors.