114898-40-7Relevant articles and documents
New 4-aryl-1,3,2-oxathiazolylium-5-olates: Chemical synthesis and photochemical stability of a novel series of S-nitrosothiols
Eilertsen, Monica,Allin, Steve M.,Pearson, Russell J.
, p. 1106 - 1110 (2018/02/28)
S-nitrosothiols (RSNOs) remain one of the most popular classes of NO-donating compounds due to their ability to release nitric oxide (NO) under non-enzymatic means whilst producing an inert disulphide by-product. However, alligning these compounds to the different biological fields of NO research has proved to be problematic due to the inherent instability of such compounds under a variety of conditions including heat, light and the presence of copper ions. 1,3,2-Oxathiazolylium-5-olates (OZOs) represent an interesting subclass of S-nitrosothiols that lock the –SNO moiety into a five membered heterocyclic ring in an attempt to improve the compound's overall stability. The synthesis of a novel series of halogen-containing OZOs was comprehensively studied resulting in a seven-step route and overall yields ranging between 21 and 37%. The photochemical stability of these compounds was assessed to determine if S-nitrosothiols locked within these mesoionic ring systems can offer greater stability and thereby release NO in a more controllable fashion than their non-cyclic counterparts.
Study of the Rh2(OAc)4- or BF3·OEt2-mediated reaction of thioacetic S-acid with α-diazocarbonyl compounds
Yao, Wengang,Liao, Mingyi,Zhang, Xiaomei,Xu, Hao,Wang, Jianbo
, p. 1784 - 1788 (2007/10/03)
The Rh2(OAc)4-catalyzed reaction of methyl aryldiazo-acetates with thioacetic S-acid gives exclusively the S-H insertion products in high yields, while the corresponding reaction mediated by BF3·OEt2 gives O-est
Thiazolidin-4-one derivatives and acid addition salts thereof
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, (2008/06/13)
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