1154739-81-7

Upstream product

• 943436-51-9 1-(4-bromo-3-methylphenyl)-3-(3,5-dichlorophenyl)-3-hydroxy-4,4,4-trifluorobutane-1-one 
• 1311202-21-7 Br^(1-)*C₂₇H₂₃BrOP⁽¹⁺⁾ 
• 130336-16-2 3,5-dichloro-2,2,2-trifluoroacetophenone 
• 1427274-98-3 tert-butyl 4-carbamoyl-2-methyl-benzoate 
• 864725-22-4 1,3-dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene 
• 1427274-47-2 tert-butyl 2-methyl-4-(2-oxo-1,3,4-oxathiazol-5-yl)benzoate 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 21900-45-8 4-bromo-2-methylbenzoyl chloride 
• 445003-37-2 4-bromo-2-methyl-benzoic acid tert-butyl ester 
• 1164268-75-0 tert-butyl 4-formyl-2-methyl-benzoate 
• 1427274-96-1 4-tert-butoxycarbonyl-3-methyl-benzoic acid 
• 5707-04-0 Phenylselenyl chloride 

Downstream Products

• 1154739-77-1 (R)-3-(4-bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole 
• 1154739-79-3 (S)-3-(4-bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole 
• 1427274-53-0 3-benzylsulfanyl-1-(4-bromo-3-methyl-phenyl)-3-(3,5-dichloro-phenyl)-4,4,4-trifluoro-butan-1-one 
• 1427274-62-1 3-(4-bromo-3-methyl-phenyl)-5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isothiazole 
• 1427274-60-9 1-(4-bromo-3-methyl-phenyl)-3-(3,5-dichloro-phenyl)-4,4,4-trifluoro-3-mercapto-butan-1-one 
• 1427274-73-4 4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isothiazol-3-yl]-2-methyl-benzoic acid butyl ester 
• 1380297-58-4 (R)-4-(4-bromo-3-methylphenyl)-2-(3,5-dichlorophenyl)-4-oxo-2-(trifluoromethyl)butanenitrile 

Relevant academic research and scientific papers

AgF-mediated fluorinative cross-coupling of two olefins: Facile access to α-CF3 alkenes and β-CF3 ketones

A AgF-mediated fluorination with a concomitant cross-coupling between a gem-difluoroolefin and a non-fluorinated olefin is reported. This highly efficient method provides facile access to both α-CF3 alkenes and β-CF3 ketones, which otherwise remain challenging to be directly prepared. The application of this method is further demonstrated by the synthesis of bioactive isoxazoline derivatives. This approach represents a conceptually novel route to trifluoromethylated compounds that combines the in situ generation of the CF3 moiety and a C-H functionalization in a single reaction system.

ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS

The present invention provides compounds of formula (I) wherein P is P0, heterocyclyl or heterocyclyl substituted by one to five Z formula (II); Y1, Y2, Y3 and Y4 are independently of each other C-H, C-R5/

Enantioselective synthesis of trifluoromethyl-substituted 2-isoxazolines: Asymmetric hydroxylamine/enone cascade reaction

(Figure Presented) Cuts both ways: The title reaction consists of an addition/cyclization/dehydration sequence and affords the biologically important chiral 3,5-diaryl-5-(trifluoromethyl)-2-isoxazolines 1 in excellent yields with high ee values. The flexi

1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF

There is provided a novel process intermediate represented by the general formula (1) or (2): (where, X represents halogen atom, cyano group or the like, Y represents halogen atom, cyano group or the like, R1 represents C1-C6/s