115482-82-1Relevant academic research and scientific papers
Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1- arylethanones
Chen, Jianzhong,Liu, Delong,Butt, Nicholas,Li, Chao,Fan, Dongyang,Liu, Yangang,Zhang, Wanbin
, p. 11632 - 11636 (2013/11/06)
First hand: The first example of a palladium-catalyzed asymmetric hydrogenation of α-acyloxy ketones (1) was accomplished to give the hydrogenated products 2 with by far the highest catalytic efficiency in up to quantitative conversions and excellent enantioselectivities. The hydrogenated products could serve as important intermediates for the preparation of many drug candidates. TFE=2,2,2-trifluoroethanol. Copyright
Enzymatic Resolution of 1,2-Diols: Comparison between Hydrolysis and Transesterification Reactions
Bosetti, Aldo,Bianchi, Daniele,Cesti, Pietro,Golini, Paolo,Spezia, Sandro
, p. 2395 - 2398 (2007/10/02)
A new practical procedure for the enzymatic resolution of 1,2-diols 1a-e has been developed by lipase-catalysed regio- and enantio-selective esterification using anhydrides as acylating agents in organic solvents.
