1155-37-9

Basic information

• Product Name: 1H-Benzimidazole,2,2'-dithiobis-
• Synonyms: Benzimidazole,2,2'-dithiobis- (6CI,7CI); 2,2'-Dibenzimidazolyl disulfide;2,2'-Dithiobis(benzimidazole); 2,2'-Dithiobis[1H-benzimidazole];2,2'-Dithiodibenzimidazole; 2-Mercaptobenzimidazolyl disulfide;Bis(2-benzimidazolyl) disulfide; Dibenzimidazol-2-yl disulfide;Dibenzimidazolyl disulfide; NSC 35825
• CAS NO: 1155-37-9
• Molecular Formula: C14H10 N4 S2
• Molecular Weight: 298.392
• Mol File: 1155-37-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 616°Cat760mmHg
• Flash Point: 326.4°C
• Density: 1.56g/cm³
• CAS DataBase Reference: 1H-Benzimidazole,2,2'-dithiobis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2,2'-dithiobis-(1155-37-9)
• EPA Substance Registry System: 1H-Benzimidazole,2,2'-dithiobis-(1155-37-9)

Safety Data

• Hazardous Substances Data: 1155-37-9(Hazardous Substances Data)

Usage

Structure

A benzimidazole derivative with two sulfur atoms bridging two nitrogen atoms

Usage

Building block in the synthesis of pharmaceuticals, agrochemicals, and industrial chemicals

Biological activities

Antifungal, antiviral, and antioxidant properties

Potential applications

Treatment of neurodegenerative diseases and certain types of cancer

Safety

Should be handled with care and used in accordance with proper safety protocols due to its potential hazardous nature.

Upstream product

• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 19829-29-9 4-pyridinethione 
• 10544-50-0 sulfur 
• 7440-57-5 gold 
• 134469-07-1 Benzimidazol-2-thiol 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 22902-32-5 2-methyl-3-phenylbenzo[4,5]imidazo[2,1-b]thiazole 
• 59940-07-7 Benzimidazol-2-ylsulfonic acid chloroanhydride 
• 134469-07-1 Benzimidazol-2-thiol 
• 51-17-2 benzoimidazole 
• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 87504-17-4 2-cyclohexylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 72885-89-3 3-phenylimino-3H-benzimidazo<2,1-c><1,2,4>-dithiazole 
• 72885-92-8 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one 
• 135430-13-6 2-<(((4-(benzyloxycarbonyl)glycyl)amino-3-phenylisothiazol-5-yl)methyl)thio>-1H-benzimidazole 

Relevant articles and documents

Cooperative Ligands in Dissolution of Gold

Development of new, environmentally benign dissolution methods for metallic gold is driven by needs in the circular economy. Gold is widely used in consumer electronics, but sustainable and selective dissolution methods for Au are scarce. Herein, we describe a quantitative dissolution of gold in organic solution under mild conditions by using hydrogen peroxide as an oxidant. In the dissolution reaction, two thiol ligands, pyridine-4-thiol and 2-mercaptobenzimidazole, work in a cooperative manner. The mechanistic investigations suggest that two pyridine-4-thiol molecules form a complex with Au0 that can be oxidized, whereas the role of inexpensive 2-mercaptobenzimidazole is to stabilize the formed AuI species through a ligand exchange process. Under optimized conditions, the reaction proceeds vigorously and gold dissolves quantitatively in two hours. The demonstrated ligand-exchange mechanism with two thiols allows to drastically reduce the thiol consumption and may lead to even more effective gold dissolution methods in the future.

Photochemistry of Pesticides, 12. On the Photoconversion of 1,3-Dihydro-2-benzimidazole-2-thione, 2(3)-Benzothiazolethione, and 2-Chlorobenzothiazole

The photoreactivity of 1,3-dihydro-2-benzimidazole-2-thione (1a) and 2(3)-benzothiazolethione (1b) has been studied in several solvents in the presence of oxygen with or without methylene blue as a sensitizer.The corresponding disulfides (5a, b), 2-oxo derivatives (2a, b), benzimidazole and benzothiazole (11a, b), and elemental sulfur have been characterized as the main products.The UV irradiation of the disulfides 5a, b results in the formation of the same product pattern as the thiones 1a, b.Photolysis of 2-chlorobenzothiazole (12) in acetonitrile gives a mixture of 2b, 2,2'-dibenzothiazole (13), while photolysis of 12 in ethanol yields 2b and 11b.Products and mechanisms are discussed and compared with previous studies in this area. - Key words: 1,3-Dihydro-2-benzimidazole-2-thione, 2(3)-Benzothiazolethione, 2-Chlorobenzothiazole, Photodegradation, Photooxidation