1155264-46-2Relevant academic research and scientific papers
SINGLE MOLECULE COMPOUNDS PROVIDING MULTI-TARGET INHIBITION OF BTK AND OTHER PROTEINS AND METHODS OF USE THEREOF
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Paragraph 0179; 0197, (2020/02/16)
The invention relates to compounds useful for inhibiting BTK and at least one other protein and to methods of treating diseases including cancer by administration of a compound(s) of Formula I-IV or pharmaceutically acceptable salts thereof as defined her
SYK INHIBITORS
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Paragraph 3283; 3285-3287, (2016/10/07)
The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)
Burton's tyrosine kinase inhibitor
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, (2017/01/17)
The invention provides a Burton's tyrosine kinase inhibitor. Particularly, a compound capable of serving as the Btk inhibitor is obtained through a wide and thorough research. It is shown through experimental results that the compound has a good inhibitin
MK2 INHIBITORS AND USES THEREOF
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, (2014/10/03)
The present invention provides compounds, compositions thereof, and methods of using the same.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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, (2010/12/01)
Compounds of formula I wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 112, (2009/06/27)
The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection
