115663-18-8Relevant academic research and scientific papers
NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Page 76, (2010/02/06)
The present invention relates to novel tricyclic compounds useful for the treatment of inflammatory conditions, diseases of the central nervous and insulin resistant diabetes.
A NEW ROUTE TO 1-OXYGENATED CARBAZOLES. SYNTHESIS OF THE CARBAZOLE ALKALOIDS MURRAYAFOLINE-A AND MURRAYAQUINONE-A
Martin, Tracey,Moody, Christopher J.
, p. 235 - 240 (2007/10/02)
1-Oxygenated carbazoles are prepared in 4 steps from indole-2-carboxylates by condensation with γ-butyrolactones to give the lactones (12), followed by hydrolysis with concomitant decarboxylation to the alcohols (13), and oxidation to the aldehydes (14).The aldehydes (14) cyclise to 1-methoxycarbazoles on treatment with boron trifluoride-methanol or with methanolic hydrogen chloride.The methoxycarbazoles (15a) and (4) were converted into the corresponding carbazolequinones (18) and (7) by demethylation, and oxidation.The carbazole alkaloids murrayafoline-A (4) and murrayaquinone-A (7) were prepared.
A NEW ROUTE TO 1-OXYGENATED CARBAZOLES. SYNTHESIS OF MURRAYAFOLINE-A
Martin, Tracey,MoodY, Christopher J.
, p. 5841 - 5842 (2007/10/02)
1-Oxygenated carbazoles are prepared in four steps from indole-2-carboxylates by Claisen condensation with butyrolactones, followed by hydrolysis with concomitant decarboxylation, oxidation, and ring closure (Scheme 2); the route is applied to the synthes
