115757-30-7

Upstream product

• 42151-56-4 (1S,2R)-(+)-N-methylephedrine 
• 79-03-8 propionyl chloride 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 110201-12-2 (2S,3R)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester 
• 110201-12-2 (2R,3R)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester 
• 110201-12-2 (2S,3S)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester 
• 110201-12-2 (2R,3S)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester 
• 79026-61-2 (R)-3-benzyloxy-2-methylpropanal 
• 115887-59-7 (1S,2R)-N-methylephedrine propionate derived E silyl ketene acetal 

Relevant academic research and scientific papers

Determination of absolute configuration using kinetic resolution catalysts

A new method was developed to assign the absolute configuration of molecules using kinetic resolution catalysts. Secondary alcohols were acylated in the presence of Birman's S-HBTM and R-HBTM catalysts, and the fast-reacting catalyst was identified by NMR

AUXILIARY SRTUCTURE AND ASYMMETRIC INDUCTION IN THE "MUKAIYAMA-ALDOL" REACTIONS OF CHIRAL SILYL KETENE ACETALS

A variety of chiral auxiliaries R*OH were prepared and tested for levels of asymmetric induction control in the "Mukaiyama-aldol" reaction of chiral silyl ketene acetals.Structural features required for high levels of control are discussed.