115765-00-9

Basic information

• Product Name: 8-chloro-6-(3,4-dimethoxyphenyl)-1-[(methylsulfanyl)methyl]-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
• CAS NO: 115765-00-9
• Molecular Formula: C₂₀H₁₉ClN₄O₂S
• Molecular Weight: 414.9085
• Mol File: 115765-00-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 596.8°C at 760 mmHg
• Flash Point: 314.7°C
• Density: 1.38g/cm³
• Vapor Pressure: 3.31E-14mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: 8-chloro-6-(3,4-dimethoxyphenyl)-1-[(methylsulfanyl)methyl]-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-chloro-6-(3,4-dimethoxyphenyl)-1-[(methylsulfanyl)methyl]-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine(115765-00-9)
• EPA Substance Registry System: 8-chloro-6-(3,4-dimethoxyphenyl)-1-[(methylsulfanyl)methyl]-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine(115765-00-9)

Safety Data

• Hazardous Substances Data: 115765-00-9(Hazardous Substances Data)

Upstream product

• 74085-88-4 ethyl(methylthio)acetic hydrazide 
• 115103-03-2 7-chloro-5-(3,4-dimethoxyphenyl)-1,3-dihydro-1,4-benzodiazepin-2-thione 
• 100-00-5 4-chlorobenzonitrile 
• 105278-82-8 5-chloro-3',4'-dimethoxy-2-(phthalimidoacetamido)benzophenone 
• 105278-81-7 7-chloro-5-(3,4-dimethoxyphenyl)-1,3-dihydro-1,4-benzodiazepin-2-one 
• 94100-08-0 5-chloro-3-(3,4-dimethoxyphenyl)-2,1-benzisoxazole 
• 94100-07-9 2-amino-5-chloro-3',4'-dimethoxybenzophenone 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Relevant articles and documents

REACTIONS OF 4-CHLORO-1-NITROBENZENE WITH (3-CHLORO-4-METHOXYPHENYL)ACETONITRILE AND (3,4-DIMETHOXYPHENYL)ACETONITRILE; SYNTHESIS OF 8-CHLORO-1-METHYL (AND METHYLTHIOMETHYL)-6-(3,4-DISUBSTITUTED PHENYL)-4H-s-TRIAZOLO-1,4-BENZODIAZEPINES

Reactions of 4-chloro-1-nitrobenzene with (3-chloro-4-methoxyphenyl)acetonitrile and (3,4-dimethoxyphenyl)acetonitrile in methanolic potassium hydroxide gave the corresponding 3-aryl-5-chloro-2,1-benzisoxazoles Ia and Ib in good yields; compounds Va, Vb, VI-VIII, and X were isolated as by-products and identified by means of spectra.Compounds Ia and Ib were transformed in five steps to the title componds XVab and XVIab which were found inactive in tests for central depressant and anticonvulsant activity.