115998-31-7Relevant academic research and scientific papers
Synthesis of 7H-tetrazolo[1,5-c]pyrrolo[3,2-e]pyrimidines and their reductive ring cleavage to 4-aminopyrrolo[2,3-d]pyrimidines
Dave, Chaitanya G.,Shah, Rina D.
, p. 1295 - 1300 (2007/10/03)
Some new 7,9-disubstituted 7H-1,2,3,4-tetrazolo[1,5-c]pyrrolo[3,2- e]pyrimidines 5 have been synthesized either by diazotization of 4-hydrazino- 5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 4 obtained by hydrazinolysis of 4-chloro-5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 3 or via a substitution reaction between 3 and sodium azide. 5,7-Disubstituted-7H- pyrrolo[2,3-d]pyrimidin-4(3H)-ones 2 were obtained by cyclocondensation of 2- amino-3-cyano-1,4-disubstituted pyrroles 1 with formic acid which on chlorination using phosphorus oxychloride afforded 3. A novel route for the synthesis of 4-amino-5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 6 by the reductive ring cleavage of 5 has been reported.
Pyrrolopyrimidines 7. Synthesis of Some New Pyrrolopyrimidin-4-amines and Other Related Derivatives With Molluscicidal Properties.
Basyouni, Wahid M.,El-Bayouki, Khairy A. M.,El-Sayed, Nortada M.,Hosni, Hanan
, p. 801 - 814 (2007/10/03)
Alkylation of 5-(p-chlorophenyl)-7-(p-tolyl)-7H-pyrrolopyrimidin-4-amine 3 with alkyl iodides afforded the 3-alkylpyrrolopyrimidinium iodide salts 6 rather than the 1-alkyl salts 4.Upon treating products 6 with alkali, the rearranged N-alkyl
