1160112-01-5

Basic information

• Product Name: (E)-1-methoxy-2- (2-phenylprop-1-en-1-yl)benzene
• Synonyms: (E)-1-methoxy-2- (2-phenylprop-1-en-1-yl)benzene
• CAS NO: 1160112-01-5
• Molecular Weight: 224.302
• Mol File: 1160112-01-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-1-methoxy-2- (2-phenylprop-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-methoxy-2- (2-phenylprop-1-en-1-yl)benzene(1160112-01-5)
• EPA Substance Registry System: (E)-1-methoxy-2- (2-phenylprop-1-en-1-yl)benzene(1160112-01-5)

Safety Data

• Hazardous Substances Data: 1160112-01-5(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 767-99-7 2-phenylbut-2-ene 
• 3698-28-0 2-allylanisole 
• 17763-67-6 Phenyl triflate 
• 100-66-3 methoxybenzene 
• 98-83-9 isopropenylbenzene 
• 591-50-4 iodobenzene 
• 66021-98-5 (o-methoxyphenyl)-1-propyne 

Relevant articles and documents

Dual ligand-promoted palladium-catalyzed nondirected C-H alkenylation of aryl ethers

Direct C-H functionalization of aryl ethers remains challenging owing to their low reactivity and selectivity. Herein, a novel strategy for nondirected C-H alkenylation of aryl ethers promoted by a dual ligand catalyst was demonstrated. This catalytic system readily achieved the highly efficient alkenylation of alkyl aryl ethers (anisole, phenetole, n-propyl phenyl ether, n-butyl phenyl ether and benzyl phenyl ether), cyclic aryl ethers (1,4-benzodioxan, 2,3-dihydrobenzofuran, dibenzofuran), and diphenyl oxides. Moreover, the proposed methodology was successfully employed for the late-stage modification of complex drugs containing the aryl ether motif. Interestingly, the compounds developed herein displayed fluorescent properties, which would facilitate their biological applications.

Carbonyl–Olefin Cross-Metathesis Through a Visible-Light-Induced 1,3-Diol Formation and Fragmentation Sequence

A visible-light-mediated approach to carbonyl–olefin cross-metathesis is described. Photoinduced hole catalysis was used to promote the formation of 1,3-diols from aldehydes and styrenes, which were then readily fragmented under acidic conditions to form the cross-metathesis products. The use of 1,3-diols as intermediates, rather than the energetically more demanding oxetanes, provides a new, orthogonal mechanistic strategy for carbonyl–olefin cross-metathesis. Furthermore, this approach does not require any metals, ligands, or additives, and provides the products with high levels of E selectivity. A mechanistic rationale is provided and supported by both theoretical calculations and experiments. Additionally, a practical synthesis of a new acridinium-based photocatalyst, including full characterization, is presented.