116129-86-3

Usage

Uses

Used in Organic Synthesis:
(E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid is used as a building block in organic synthesis for creating more complex molecules. Its unique structure allows for further chemical modifications and the development of novel compounds with specific properties and applications.
Used in Pharmaceutical Industry:
(E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid is used as a potential pharmaceutical compound due to the presence of butenoic acid, which is found in various natural products with biological activity. (E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid's phenyl and carbethoxyethyl substituents may enhance its pharmaceutical potential by affecting its solubility, reactivity, and stability.
Used in Biological Research:
(E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid is used as a subject of study in biological research to explore its potential biological activity and possible applications in medicine. (E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid's structure may provide insights into the development of new drugs or therapies based on its interactions with biological systems.

Upstream product

• 23360-63-6 triphenyl-(α-carbethoxy-β-carboxyethyl)phosphonium betaine 
• 100-52-7 benzaldehyde 
• 77924-28-8 4-tert-butyl 1-ethyl 2-(diethoxyphosphoryl)succinate 
• 123-25-1 succinic acid diethyl ester 
• 1031223-86-5 2-[1-Phenyl-meth-(E)-ylidene]-succinic acid 4-tert-butyl ester 1-ethyl ester 

Downstream Products

• 33295-46-4 ethyl 4-acetoxynaphthalene-2-carboxylate 
• 116129-77-2 N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-4-morpholin-4-yl-4-oxo-2-[1-phenyl-meth-(E)-ylidene]-butyramide 
• 116129-75-0 (E)-2-<(4-morpholinylcarbonyl)methyl>-trans-cinnamic acid 
• 116129-87-4 ethyl 2-<(4-morpholinylcarbonyl)methyl>-trans-cinnamate 

Relevant academic research and scientific papers

Synthesis and photochromic properties of methoxy substituted 2,2-diaryl-2H-naphtho[1,2-b]pyrans

A series of methoxy-substituted 2,2-di(4-methoxyphenyl)-2H-naphtho[1,2-b]pyrans has been synthesised from 3-alkoxycarbonyl-1-naphthols and 1,1-di(4-methoxyphenyl)prop-2-yn-1-ol. The influence of the methoxy group on the wavelength of maximum absorption an

An efficient method for the synthesis of substituted 4-acetoxynaphthalene- 2-carboxylate esters, ethyl 4-acetoxybenzofuran-6-carboxylate, and ethyl 4-acetoxybenzothiophene-6-carboxylate

4-Acetoxynaphthalene-2-carboxylate esters and their corresponding benzofuran and benzothiophene esters are important synthetic intermediates for the preparation of analogs of CC-1065 and the duocarmycins. In this communication, an efficient method for the synthesis of the titled compounds using an Emmons-Horner reaction strategy is reported. As an alternative to the Stobbe condensation reaction, coupling of tert-butyl 3-ethoxycarbonyl-3- (phosphonodiethyl)propionate with a series of aromatic aldehydes, followed by acid promoted removal of the tert-butyl group and Friedel-Crafts reaction, produced the target compounds in good overall yields and of excellent quality.

Studies on the Synthesis of highly substituted naphthol: Preparation of 6-Hydroxy-5,7-Dimethoxy-2-Naphthoic Acid, Isolated From Ulmus Thomasii

An improvement of a known procedure, affording substituted 4-hydroxy-2-naphthoic acid derivatives from aromatic aldehydes is described and its general applicability is shown through the preparation of a natural naphthalene derivative isolated from Ulmus thomasii.

tert-Butyl-3-carboxyethyl-3-phosphonodiethylpropionate. A novel reagent for Stobbe-like condensations

tert-Butyl-3-carboxyethyl-3-phosphonodiethylpropionate was prepared and reacted with a range of aldehydes to give, after hydrolysis, itaconic half esters.