33295-46-4

Upstream product

• 96181-46-3 3-(ethoxycarbonyl)-4-phenylbut-3-enoic acid 
• 108-24-7 acetic anhydride 
• 116129-86-3 (E)-4-phenyl-3-carbethoxyethylbut-3-enoic acid 
• 127-09-3 sodium acetate 

Downstream Products

• 188863-65-2 (4-(benzyloxy)naphthalen-2-yl)methanol 
• 851077-04-8 4-(benzyloxy)-2-naphthaldehyde 
• 188863-64-1 ethyl 4-(benzyloxy)-2-naphthoate 
• 91307-39-0 ethyl 1,2,3,4-tetrahydro-4-hydroxy-2-naphthoate 
• 216310-14-4 Methanesulfonic acid 5-benzyloxy-3-methoxy-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-ylmethyl ester 
• 216310-12-2 (5-Benzyloxy-3-methoxy-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-yl)-methanol 
• 216310-04-2 4-Benzyloxy-1-bromo-naphthalene-2-carboxylic acid ethyl ester 
• 216310-09-7 4-Benzyloxy-1-bromo-2-(1-methoxy-but-3-enyl)-naphthalene 
• 216310-10-0 5-Benzyloxy-3-methoxy-1-methylene-2,3-dihydro-1H-cyclopenta[a]naphthalene 
• 216310-08-6 1-(4-Benzyloxy-1-bromo-naphthalen-2-yl)-but-3-en-1-ol 

Relevant academic research and scientific papers

MCL-1 INHIBITORS AND METHODS OF USE THEREOF

Disclosed are Mcl-1 inhibitors, pharmaceutical compositions comprising the same and methods of using the same.

Synthesis and photochromic properties of methoxy substituted 2,2-diaryl-2H-naphtho[1,2-b]pyrans

A series of methoxy-substituted 2,2-di(4-methoxyphenyl)-2H-naphtho[1,2-b]pyrans has been synthesised from 3-alkoxycarbonyl-1-naphthols and 1,1-di(4-methoxyphenyl)prop-2-yn-1-ol. The influence of the methoxy group on the wavelength of maximum absorption an

An efficient method for the synthesis of substituted 4-acetoxynaphthalene- 2-carboxylate esters, ethyl 4-acetoxybenzofuran-6-carboxylate, and ethyl 4-acetoxybenzothiophene-6-carboxylate

4-Acetoxynaphthalene-2-carboxylate esters and their corresponding benzofuran and benzothiophene esters are important synthetic intermediates for the preparation of analogs of CC-1065 and the duocarmycins. In this communication, an efficient method for the synthesis of the titled compounds using an Emmons-Horner reaction strategy is reported. As an alternative to the Stobbe condensation reaction, coupling of tert-butyl 3-ethoxycarbonyl-3- (phosphonodiethyl)propionate with a series of aromatic aldehydes, followed by acid promoted removal of the tert-butyl group and Friedel-Crafts reaction, produced the target compounds in good overall yields and of excellent quality.