1161831-76-0

Basic information

• Product Name: 1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea
• Synonyms: 1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea
• CAS NO: 1161831-76-0
• Molecular Weight: 476.542
• Mol File: 1161831-76-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea(1161831-76-0)
• EPA Substance Registry System: 1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea(1161831-76-0)

Safety Data

• Hazardous Substances Data: 1161831-76-0(Hazardous Substances Data)

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 1161831-73-7 1-[(R)-1-(3,4-dihydro-2H-pyran-2-yl)methyl]-3-(2-dimethylamino-ethyl)-urea 
• 100-52-7 benzaldehyde 

Downstream Products

• 858668-07-2 EMD 534085 
• 1161831-75-9 endo-1-(2-dimethylamino-ethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)-urea 

Relevant articles and documents

PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES

The invention relates to a novel process for preparing enantiomerically enriched or pure tetrahydroquinoline derivatives by reacting a chiral dihydropyran-methylamine C with a aldehyde B and an aniline A in a multicomponent one pot synthesis in the presen